ea0037ep77 | Adrenal cortex | ECE2015
Lang Katharina
, Weber Katrin
, Quinkler Marcus
, Dietz Anna
, Wallaschofski Henri
, Hannemann Anke
, Vonend Oliver
, Willenberg Holger
, Reincke Martin
, Allolio Bruno
, Hahner Stefanie
Context: Primary aldosteronism (PA) is the most common cause of secondary hypertension. Aldosterone excess can cause oxidative stress and respectively DNA damage in vitro and in vivo and increased levels of oxidative stress have been demonstrated in PA patients. Single case reports describe a coincidence of PA with renal cell carcinoma (RCC) and other tumours. However, so far no data on the prevalence of benign and malignant neoplasms in patients with PA exis...