Searchable abstracts of presentations at key conferences in endocrinology

ea0035p783 | Obesity | ECE2014

Decreased expression of genes encoding thermogenesis-related proteins in adipose tissues of obese patients is not associated with their methylation status

Kurylowicz Alina , Jonas Marta , Lisik Wojciech , Jonas Maurycy , Wicik Zofia Agnieszka , Wierzbicki Zbigniew , Chmura Andrzej , Puzianowska-Kuznicka Monika

Introduction: Thermogenesis constitutes an important part of energy expenditure and its disturbances may contribute to the development of obesity. The aim of this study was to investigate whether the expression of thermogenesis-related genes differs in adipose tissues of obese and normal-weight individuals and if methylation of CpG islands located in the regulatory regions of these genes is involved in this phenomenon.Materials and methods: The expressio...