Endocrine Abstracts

Introduction: Adrenocortical carcinoma (ACC) is a rare and aggressive tumor. Mitotane has been the mainstay adjuvant therapy of ACC. The study aimed to describe patients diagnosed with precocious puberty (PP) and other endocrinological disorders during mitotane treatment.Material and methods: This retrospective study enrolled four children with ACC treated with mitotane complicated by PP. The patients were diagnosed at C...