Searchable abstracts of presentations at key conferences in endocrinology

ea0029s8.2 | Global phenotypes of endocrine disease | ICEECE2012

Ethnic specific PCOS

Wijeyaratne C.

PCOS is the commonest endocrine disorder of young women. It has appreciable impact on wellbeing and quality of life, fertility and reproduction, and long term metabolic and cancer risks. Acknowledged a ‘condition of our times’, there was no data from Asia until recently. South Asians have early manifestation with more severe symptoms than white Europeans. Young affected Asians have significantly greater insulin resistance than older white Europeans; with approximatel...

ea0005p105 | Diabetes, Metabolism and Cardiovascular | BES2003

Polycystic ovary syndrome (PCOS) in Sri Lankans

Wijeyaratne C , Balen A , Barth J , Belchetz P

PCOS has major long-term health implications that are closely linked to the Metabolic Syndrome. The prevalence of the Metabolic Syndrome is high among migrant and indigenous South Asian populations. We have previously demonstrated that migrant South Asians with PCOS have a greater degree of insulin resistance than white Europeans with PCOS. As there is a paucity of data on PCOS among indigenous South Asian populations, consecutive consenting anovular PCOS subjects (80) and age...

ea0003p212 | Reproduction | BES2002

Phenotype and insulin resistance (IR) in polycystic ovary syndrome (PCOS) among South Asians (SA) and Caucasians (C): Is there a difference?

Wijeyaratne C , Balen A , Barth J , Belchetz P

Background: PCO is more prevalent among SA than C and IR is central to its pathogenesis; whilst Type 2 diabetes (DM) is commoner in SA. We compared the phenotype and IR in South Asian and Caucasians with PCOS.Methods: Comparison of consecutive anovular PCOS; 47 SA and 36 Caucasians and their age and weight matched controls (11 SA and 22 Cs).Results: SA presented earlier (age 26 plus/minus 4 v 30.1 plus/minus 5, p = 0.005). BMI (24....