Searchable abstracts of presentations at key conferences in endocrinology

ea0058p076 | Diabetes | BSPED2018

Feeding and autoimmunity in down’s syndrome evaluation study (FADES)

Williams Georgina , Mortimer Georgina , Gillespie Kathleen , Hamilton-Shield Julian

Introduction: Children with DownÂ’s Syndrome (DS) have altered immunity with higher rates of diabetes, thyroid autoimmunity, coeliac disease, respiratory tract infections and leukemia. Diabetes in children with DS appears to be accelerated with an earlier age of onset compared with the general population, with 22% diagnosed before the age of 2 years. Increased HLA class II DR3/4 susceptibility is seen in in children with DS and diabetes but the prevalence is reduced compar...

ea0033p66 | (1) | BSPED2013

Chronic kidney disease: an uncommon cause of galactorrhoea in an adolescent

Williams Georgina , Inward Carol , Tizzard E Jane , Burren Christine

Introduction: Hyperprolactinaemia may occur in 30% of adults with chronic kidney disease (CKD), although rare in paediatrics. The pathophysiology might be further complicated by pre-existing pituitary abnormalities.Case: Symptomatic hyperprolactinaemia developed in this adolescent girl with CKD and hypopituitarism. History involved neonatal hypoxic ischaemic encephalopathy (HIE) and renal cortical necrosis. CKD Stage 3 ensued. Growth declined by 2.3 year...

ea0078p46 | Obesity | BSPED2021

Liraglutide with lifestyle modifications causing rapid weight loss in an adolescent with morbid obesity and life threatening sleep apnoea

Williams Georgina , Easter Shelley , Langton Hewer Simon C , Shield Julian P. H. , Giri Dinesh

Introduction: The management of childhood obesity is complex and requires intensive input from a multidisciplinary team. Pharmaceutical interventions may be required in addition to lifestyle modifications to treat morbid obesity. In a double blind randomised controlled trial, liraglutide, a glucagon-like peptide 1 (GLP-1) agonist along with dietary and lifestyle interventions showed beneficial BMI reduction in children and adolescents. We present a morbidly obese adolescent wi...

ea0085oc10.6 | Oral Communications 10 | BSPED2022

A comparative study observing the association between graves’ disease and the covid-19 pandemic in children

Uppal Kamalpreet , Warner Justin , Williams Georgina , Pryce Rebekah , Hawkes Davida , Bindu Avatapalle Hima

Background: Coronavirus 2019 (Covid-19), an infectious disease caused by SARS-CoV-2 virus has been linked to autoimmunity. GravesÂ’ disease (GD) is a common subtype of paediatric hyperthyroidism and an autoimmune condition, where antibodies stimulate the thyroid-stimulating hormone receptor on the thyroid gland to produce excess thyroid hormone. Although, paediatric GD is rare, incidence have risen before the pandemic, and this rise has accelerated since the Covid-19 pande...