Searchable abstracts of presentations at key conferences in endocrinology

ea0008s4 | Basic Science Review Lecture | SFE2004

Understanding endocrine development of the human beta cell: guiding stem cell therapy for Type 1 Diabetes

Piper K , Dunleavey L , Cameron I , Wilson D , Hanley N

Stem cell therapy offers a far-sighted opportunity to cure Type 1 diabetes. To achieve this ambitious goal, an in depth understanding of how human beta cells normally develop is critical, as it provides the perfect model for the differentiation of stem cells down normal safe developmental pathways. Our data provide a framework of human pancreas development and islet formation, highlighting subtle differences from the parallel process in mouse. Key genes have been identified th...

ea0009p166 | Thyroid | BES2005

Triiodothyronine and glucose insulin potassium individually improve cardiovascular performance post coronary artery bypass graft surgery without increasing systemic oxygen consumption

Ranasinghe A , Quinn D , Franklyn J , Graham T , Keogh B , Mascaro J , Rooney S , Wilson I , Pagano D , Bonser R

ObjectivesBoth glucose insulin potassium (GIK) and tri-iodothyronine (T3) may improve cardiovascular performance following cardiac surgery. The effects of combined treatment are unknown.MethodsAfter obtaining local research ethics committee approval, we performed a randomised double-blind placebo-controlled trial on patients undergoing first time elective/urgent isolated CABG. Between January 2000 ...