Searchable abstracts of presentations at key conferences in endocrinology

ea0035p682 | Growth hormone IGF axis basic | ECE2014

Evaluation of the effect of X chromosome abnormalities on the response to GH therapy in children with turner syndrome

Kasprzyk Jakub , Wlodarczyk Marcin , Sobolewska Aleksandra , Glusinska Sylwia , Stawerska Renata , Hilczer Maciej , Lewinski Andrzej

Introduction: Turner syndrome (TS) is a condition caused by structural or numerical abnormalities of X chromosome. Growth deficiency is characteristic for patients with TS, and particular karyotype abnormalities of the X chromosome may be associated with different responsiveness to human GH (hGH) therapy. The aim of the study was to determine the effect of TS karyotype on growth velocity during hGH therapy in TS.Methods: 23 TS patients treated with hGH w...