Endocrine Abstracts

Background: The curative therapy of primary hyperparathyroidism (pHPT) is surgery. Data about ultrasound-guided laser ablation (LA) of parathyroid tumor are limited, however it could be a solution for patients with high surgery or anesthetic risk. We report our experience on LA of parathyroid tumors in 11 patients with pHPT with high surgery or anesthetic risk.Methods: LA was performed under ultrasound guidance with an output power of 3W. Total energy an...

IntroductionTreatment of choice in acromegaly is transsphenoidal resection of GH-secreting pituitary adenoma. Its efficacy ranges from 28% to 83% depending on tumor size and location. Random GH < 1 µg/l or nadir GH in OGTT < 0.4 µg/l and normal IGF-1 are found to be the evidence of effective surgery. However, some patients diagnosed with acromegaly remission after surgery present discordant GH and IGF-1 results.Ai...

Thyroid hormones (TH) are key regulators of basal metabolic rate and body weight. They increase resting energy expenditure by increased synthesis of uncoupling protein-1 (UCP-1) in brown adipocytes which stimulates energy dissipation as a heat. TH also increase appetite by central adrenergic stimulation. Body weight change is a key symptom of thyroid dysfunction especially the weight gain observed in patients treated for hyperthyroidism AIM: To compare the influence of differe...