Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep792 | Pituitary: clinical | ECE2015

Thyroid lesions in patients with acromegaly–case-control study

Wolinski Kosma , Stangierski Adam , Gurgul Edyta , Brominska Barbara , Ruchala Marek

Introduction: Acromegaly is a disease caused by excessive secretion of growth hormone and subsequently insulin growth factor 1. It is believed that this oversecretion can cause increased prevalence of nodular goiter and thyroid cancer. However, the amount of studies comparing acromegalic patients with control groups is low. The aim of the study was to assess the prevalence of thyroid lesions in patients with acromegaly in comparison with age and sex-matched control group.<...

ea0037ep955 | Thyroid (non-cancer) | ECE2015

Shear-wave elastography in diagnostics of primary hyperparathyroidism – new application of the method

Stangierski Adam , Wolinski Kosma , Szczepanek-Parulska Ewelina , Ruchala Marek

Introduction: Shear wave elastography (SWE) is a reliable, objective and reproducible technique in sonographic assessment of tissue stiffness. It is considered to be an improvement of conventional ultrasonographic examination. It was demonstrated to be useful in the diagnosis of many thyroid disorders, such as thyroid cancer, Hashimoto’s thyroiditis or Graves’ disease. The aim of our study was to check if SWE can be supportive in the diagnosis of primary hyperparathy...

ea0037ep1120 | Endocrine tumours | ECE2015

The prevalence of benign and malignant neoplasms in the patients with acromegaly

Stangierski Adam , Wolinski Kosma , Gurgul Edyta , Ruchala Marek

Introduction: Acromegaly is a relatively rare endocrine condition caused by GH oversecretion by pituitary adenoma. Its most frequent complications include cardiovascular and respiratory system diseases with high tendency of neoplastic transformation and increased risk of benign and malignant tumors. The aim of this retrospective study was to assess the prevalence of benign and malignant neoplasms in patients with acromegaly.Materials and methods: We have...

ea0035p36 | Adrenal cortex | ECE2014

An endocrine dilemma: adrenal tumor

Brominska Barbara , Wolinski Kosma , Cyranska-Chyrek Ewa , Szczepanek-Parulska Ewelina , Ruchala Marek

Introduction: While, both quality and accessibility to novel imaging technics rises, we observe a surge in detection of adrenal masses. Those tumors are accidentally found in ~ 0.4% of ultrasonographies and in 4% of computed tomography scans (CT) conducted due to other indications. In spite of high prevalence of those lesions approach to their diagnosis, follow-up and treatment is still controversial. High financial costs and possible adverse effect on health connected with th...

ea0035p563 | Endocrine tumours and neoplasia | ECE2014

Analysis of ultrasonographic parameters influencing thyroid nodules elasticity

Wolinski Kosma , Szczepanek-Parulska Ewelina , Stangierski Adam , Gurgul Edyta , Ruchala Marek

Introduction: Elastography is a method of tissue stiffness assessment. It was already demonstrated that thyroid cancers are less elastic than benign lesions. However, little is known about other factors, which might influence the stiffness of thyroid nodules and disrupt the prediction of malignancy using this technique. The aim of this study was to conduct the first systematic assessment of factors potentially affecting elasticity of thyroid lesions.Meth...

ea0035p983 | Thyroid (non-cancer) | ECE2014

Role of conventional ultrasonography and shear wave elastography in selection lesions for fine needle aspiration biopsy in multinodular goiter - preliminary study

Stangierski Adam , Wolinski Kosma , Szczepanek-Parulska Ewelina , Gurgul Edyta , Ruchala Marek

Introduction: According to a high prevalence and relatively low occurrence of malignancies in thyroid nodular disease (TND), the selection of suspicious lesions for fine – needle aspiration biopsy (FNAB) seem to be a vital problem in the daily endocrinological practice. Beside deciding if the FNAB is necessary, frequently the second problem occurs – which nodule or nodules should be chosen in case of multinodular goiter (MNG), when the number of potential lesions for...

ea0041ep1073 | Thyroid (non-cancer) | ECE2016

Efficacy and safety of radioiodine therapy for mild Graves’ ophthalmopathy in dependence on nicotine consumption

Czarnywojtek Agata , Komar-Rychlicka Krzesislawa , Zgorzalewicz-Stachowiak Malgorzata , Wolinski Kosma , Stangierski Adam , Torlinska Barbara , Florek Ewa , Waligorska-Stachura Joanna , Ruchala Marek

Introduction: Graves ‘Orbitopathy (GO), is an autoimmune disease associated with Graves’ thyrotoxicosis (GT). The therapy is largely dependent on the severity and activity of ocular changes. Additionally, the severity of GO is influenced by exogenous factors, such as thyroid dysfunction, cigarette smoking or radioiodine therapy (RIT). The aim of the study was to indicate how radioiodine therapy (RIT) influences on GO in smoking and non-smoking patients.<p class="...

ea0041ep1100 | Thyroid cancer | ECE2016

Comparison of the late effects of ablation therapy with single and fractionated dose of radioiodine in patients with differentiated thyroid carcinoma

Wolinski Kosma , Czepczynski Rafal , Stangierski Adam , Trojanowski Maciej , Rewaj-Losyk Magdalena , Ziemnicka Katarzyna , Bęczyk Maciej , Dyzmann-Sroka Agnieszka , Ruchala Marek

Introduction: According to a limited number of specialized hospital beds for radioiodine therapy in some countries, fractionated dose of radioiodine may be considered as the ablation therapy of differentiated thyroid cancer (DTC). Aim of the study was to compare the late effects of ablation therapy with single and fractionated dose of radioiodine in patients with DTC.Patients and metods: Patients with DTC treated with one (131)I dose of 2.2 GBq or fracti...

ea0037ep956 | Thyroid (non-cancer) | ECE2015

The role of antithyroglobulin, antiperoxidase and anti-TSH autoantibodies in amiodarone induced thyrotoxicosis or amiodarone induced hypothyroidism (a two-center study)

Czarnywojtek Agata , Zgorzalewicz-Stachowiak Malgorzata , Fichna Marta , Wolinski Kosma , Plazinska Maria Teresa , Stangierski Adam , Gut Pawel , Miechowicz Izabela , Komarowska Hanna , Czepczynski Rafal , Krolicki Leszek , Ruchala Marek

Purpose: In the recent study it has been reported, that elevated serum concentrations of TSH receptor (TSH-R), antithyroglobulin (Tg), antiperoxidase (TPO) autoantbodies (Abs) may be observed in the subjects treated for amiodarone induced thyrotixicosis (AIT) type I, decreased in type II of AIT, or changed in amiodarone induced hypothyroidism (AIH). This study was done to analyse the changes of Tg-Abs, TPO-Abs and TSH-R-Abs titer in euthyroid, hyperthyroid (AIT), and hypothyro...

ea0035p1035 | Thyroid (non-cancer) | ECE2014

Results of preventive radioiodine therapy in euthyroid patients with history of hyperthyroidism prior to administration of amiodarone with permanent atrial fibrillation (preliminary study)

Czarnywojtek Agata , Wolinski Kosma , Gut Pawel , Czepczynski Rafal , Plazinska Maria Teresa , Kunikowska Jolanta , Kobylecka Malgorzata , Miechowicz Izabela , Krolicki Leszek , Ruchala Marek

Introduction: Radioiodine (RAI) therapy is a standard procedure in therapy of hyperthyroidism. However, the use of RAI in euthyroid patients requiring chronic administration of amiodarone (AM), in a case of lacking efficacy of other antiarrhythmic drugs might be controversial.Objective: The aim of the study was to assess the safety and efficacy of an AM therapy prior to treatment with radioiodine therapy in euthyroid patients with permanent atrial fibril...