Searchable abstracts of presentations at key conferences in endocrinology

ea0008p71 | Neuroendocrinology and behaviour | SFE2004

Ghrelin increases food intake in obese as well as lean subjects

Druce MR , Wren AM , Park A , Milton J , Patterson M , Frost G , Ghatei M , Small C , Bloom SR

The gut hormone ghrelin is involved in feeding behaviour. It increases appetite and food intake when administered by intravenous infusion to subjects of normal weight. Ghrelin levels are often lower in obese than lean individuals and whether responsiveness to ghrelin differs in lean and obese people is not known. We investigated whether obese human subjects are sensitive to the effects of ghrelin. Approval of the local ethics committee was obtained. We examined the effects of ...