Searchable abstracts of presentations at key conferences in endocrinology

ea0034p59 | Clinical practice/governance and case reports | SFEBES2014

Unexpected adrenocortical carcinoma 8 years after diagnosis of adrenal incidentaloma

Yadagiri Mahender , Barton David

Adrenal incidentalomas (AI) are incidentally discovered adrenal masses on imaging studies requested for reasons unrelated to adrenal pathology with a prevalence of 8% in autopsy and 4% in radiologic series. Although most AI are non-functioning benign adenomas, their increasing prevalence presents diagnostic and therapeutic challenges. We report a case of adrenocortical carcinoma (ACC) in an asymptomatic 83-year-old man, 8 years after being diagnosed with AI. ACC is an uncommon...

ea0038p78 | Clinical practice/governance and case reports | SFEBES2015

Pituicytoma, not a ‘meningioma’: late recurrence in a rare pituitary tumour

Yadagiri Mahender , Shaw Simon , Saravanappa Natarajan , Ayuk John , Jose Biju

Pituicytomas are rare tumours, originating from modified glial cells called pituicytes. The lineage of these tumours remains a topic of debate. Approximately 65 cases have been reported in the literature to date, since being formally recognised in 2007. We report a case where the final diagnosis was made after second surgery for late recurrence.Case: A 54-year-old man presented with left sided visual disturbances in 1998 and underwent transcranial resect...

ea0038p116 | Clinical practice/governance and case reports | SFEBES2015

Erectile dysfunction, diabetes mellitus, and sun-tan: the hypogonadism story with a difference

Yadagiri Mahender , Varadhan Laks , Jadun Changez , Jose Biju

Background: Hypogonadism and erectile dysfunction have diverse causes. Hypogonadotrophic hypogonadism results from pituitary dysfunction, often caused by pituitary adenoma, pituitary surgery, radiotherapy, or use of prescription/non-prescription drugs. Rarer causes should be considered during initial investigation of patients with erectile dysfunction. We present a case of secondary hypogonadism and how further investigations eventually led to the underlying diagnosis.<p c...

ea0049ep409 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Improving safety in diabetes management and reducing insulin errors in hospital – practically achievable or a utopian fantasy?

Burbridge Wyn , Braycotton Lynne , Puttanna Amar , Yadagiri Mahender , Ilsley Dee , Mukhopadhyay Sagnik , Munichoodappa Karthik , De Parijat

42 insulin related incidents were reported within our Trust in 2014. Subsequent Root Cause Analysis revealed numerous insulin errors, hyperglycemia mismanagement and highlighted significant deficits in diabetes knowledge amongst nursing staff. To address the above issues, new safety interventions were introduced and five key outcomes are:1. A new stand-alone insulin prescription chart introduced May’15 has seen insulin incidents dec...

ea0038p334 | Pituitary | SFEBES2015

Clinically non-functioning pituitary macroadenomas: presenting features and outcomes: recent experience at a tertiary centre

Yadagiri Mahender , Vijay Arun , Pritchard Mark , Nayak Ananth , Shaw Simon , Saravanappa Natarajan , Ayuk John , Jose Biju

Introduction: Non-functioning pituitary macroadenoma (NFMA) can cause considerable morbidity due to pituitary dysfunction and pressure effects. We present recent experience in managing cases diagnosed with NFMA at a single tertiary centre between January 2009 and October 2013.Results: Of the 63 patients with NFMA, 28 (44%) were females. Age ranged from 22 to 91 (mean 63). Visual disturbance symptoms (35/63; 57%) were the commonest presentation. Headache ...

ea0048oc4 | Oral Communications | SFEEU2017

One year efficacy, safety and tolerability outcomes of endoscopic proximal intestinal exclusion therapy using the Endobarrier device: institution of the UK’s first National Health Service Endobarrier service for type 2 diabetes and obesity

Gupta Piya Sen , Yadagiri Mahender , Irwin Susan , Burbridge Wyn , Gandhi Hardeep , Alden Rachel , Bleasdale John , Fogden Ed , Anderson Mark , Ryder Bob

Introduction: Our institution leads a UK, multicentre, randomised controlled trial (REVISE-Diabesity ISRCTN00151053) investigating the interaction of Endobarrier therapy, a 60 cm endoscopically implanted proximal intestinal liner, with glucagon-like peptide-1 drug therapy.Aims: To evaluate whether acquired experience could translate into establishment of an effective and safe NHS Endobarrier service in patients with diabesity.Metho...