Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep429 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Is thiol/disulfide homeostasis related to parity and gravidity in gestational diabetes?

Yildiz Faruk , Bicer Cemile , Senyurt Mahmut , Alisik Murat , Carlioglu Ayse

Purpose: The purpose of this study was to evaluate the relation gestational diabetes mellitus (GDM) and the thiol/disulfide balance, used as a marker of oxidative stress, by measuring that exchange using a novel technique.Material/Methods: Thirty one subjects diagnosed with GDM and 30 healthy pregnant women were included in the study. Thiol/disulfide homeostasis concentrations were measured by a newly developed method in this study. After native thiol, t...

ea0041ep373 | Clinical case reports - Thyroid/Others | ECE2016

A rare cause of hypoglycemia in a diabetic woman: insulinoma

Cadirci Kenan , Yildiz Faruk , Sevimli Hakan , Gozcu Hakan , Kaya Yasemin , Keskin Havva , Carlioglu Ayse

Insulinoma is generally a rare benign tumor of the pancreas islet cell. The typical clinical symptom of insulinoma are repetitive hypoglycemia attacks. Insulinoma with coexisting diabetes is extremely rare condition, We aim to present a case with insulinoma conmomittant with type 2 diabetes mellitus.Case report: A 65-year-old woman diagnosed with type 2 diabetes mellitus was admitted by our internal medicine clinic. She complained from perspiration and t...

ea0037ep359 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Gestational diabetes mellitus may associate with atherosclerosis due to high mean platelet volume which is a determined of platelet function

Durmaz Senay Arikan , Carlioglu Ayse , Eris Bilge , Yildiz Faruk , Kilic Halime

Aim: Mean platelet volume (MPV), which is a determinant of platelet function, is an independent risk factor for atherosclerosis. The aim of this study is to evaluate MPV values in gestational diabetes mellitus (GDM).Material and methods: Forty-nine women with gestational diabetes mellitus (mean age 28.2±4.7 years) and 40 healthy pregnant women (mean 26.2±4.6 years age) who came to our Out-Patient Clinic of Endocrinology were included in the stu...

ea0041ep629 | Endocrine tumours and neoplasia | ECE2016

Circulating levels of survivin in acromegaly

Ademoglu Esra , Candan Zehra , Gorar Suheyla , Niyazoglu Mutlu , Carlioglu Ayse , Yildiz Faruk , Baydar Idris , Sevimli Hakan , Arslan Abdulmuttalib

Introduction: Acromegaly is a chronic disorder characterized by chronic growth hormone (GH) excess. In most of cases, GH hypersecretion is derived from somatotroph cell tumors. Survivin is a member of apoptosis protein family, which was recently showed to be expressed in different benign and malignant human tumors. A number of studies showed overexpression of survivin in pituitary adenomas. This study is intended to determine circulating levels of survivin in patients with acr...

ea0041ep181 | Calcium and Vitamin D metabolism | ECE2016

Mean platelet volume in a patient with hypoparathyroidism: the relationship between metabolic syndrome, impaired fasting glucose and cardiovascular risk

Cipil Handan , Timur Ozge , Sevimli Hakan , Yildiz Faruk , Utlu Mustafa , Arslan Abdulmuttalip , Ademoglu Esra Nur , Budak Mehmet Emin , Baydar Idris , Kadi Melek , Carlioglu Ayse

Background: Parathyroid hormone (PTH) is a key regulator of mineral metabolism, the homeostasis of calcium, phospate, vitamin D and bone turnover. Hypoparathyroidism is a rare disease characterized by hypocalceamia with inappropriately low plasma levels of PTH. Mean platelet volume (MPV) is the measure of platelet size. Increased MPV has been associated with cardiovascular risk.Objective: In our preliminary study, we aim to show that untreated hypoparath...

ea0041ep696 | Female Reproduction | ECE2016

Increased uric acid levels and clinical relationship in polycystic ovary syndrome

Keskin Havva , Timur Ozge , Kaya Yasemin , Utlu Mustafa , Yildiz Faruk , Ademoglu Esra Nur , Kadi Melek , Budak Mehmet Emin , Gozcu Hakan , Sevimli Hakan , Durmaz Senay , Carlioglu Ayse , Kamalak Zeynep

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects women of reproductive age. Clinical and biochemical characteristics are similar to metabolic syndrome. Insulin resistance in patients with metabolic syndrome, is associated with serum uric acid levels. In our study, we aimed to investigate the relationship between serum uric acid levels and clinical and laboratory in PCOS patients.Materials and Method: PCOS ...

ea0041ep788 | Obesity | ECE2016

Mean platelet volume in a patient with celiac disease: the relationship between metabolic syndrome, impaired fasting glucose and cardiovascular risk

Cipil Handan , Baydar Idris , Altinkaynak Konca , Ademoglu Esra , Laloglu Esra , Filiz Murat , Sanibas Ahmet Veli , Yildiz Faruk , Sevimli Hakan , Arslan Muttalip , Arikan Senay , Carlioglu Ayse

Celiac Disease (CD) is a chronic inflammatory disorder and requires life-long treatment and follow-up. Mean platelet volume (MPV), determinant of platelet function, is an independent risk factor for cardiovascular disease (CVD). Metabolic syndrome (MS) is a multiplex risk factor that arises from insulin resistance accompanying abnormal adipose deposition and function. It is a risk factor for coronary heart disease, as well as for diabetes, fatty liver, and several cancers....

ea0041ep1028 | Thyroid (non-cancer) | ECE2016

Is the high mean platelet volume associated with inflammation in subacute thyroiditis?

Simsek Eda , Yildiz Faruk , Ademoglu Esra , Durmaz Senay Arikan , Filiz Murat , Bingol Fatih , Bingol Buket , Baykan Emine Kartal , Aydin Unsal , Sanibas Ahmet Veli , Carlioglu Ayse

Introduction and aims: Subacute thyroiditis (ST) is a spontaneous remitting inflammatory disease of thyroid gland. Although there is no clear evidence for its specific etiology, multiple factors may responsible for this inflammatory reaction. Mean platelet volume (MPV) is a new important inflammatory marker that indicates disease activity. Aim of this study is to evaluate MPV value in patients with subacute thyroiditis.Materials and methods: Thirty-one p...

ea0041ep1068 | Thyroid (non-cancer) | ECE2016

Glomerular filtration rate in euthyroid Hashimoto’s patients

Coskun Firat Yasemin , Timur Ozge , Sevinc Can , Yildiz Faruk , Kartal Baykan Emine , Aydin Unsal , Emin Budak Mehmet , Gozcu Hakan , Arslan Abdulmuttalip , Sevimli Hakan , Carlioglu Ayse

Thyroid hormones influence renal development, kidney structure, renal hemodynamics, glomerular filtration rate, the function of many transport systems along the nephron and sodium and water homeostasis. Patients with hypothryoidism can have clinically important reductions in glomerular filtration rate (GFR). 41 patients (mean age 31.5±11 years) newly diagnosed as Hashimoto thyroiditis with presence of high thyroid autoantibodies with gland heterogenity in ultrasound and a...

ea0041ep1151 | Thyroid cancer | ECE2016

Neutrophil-Lymphocyte Ratio (Nlr) and Platelet -Lymphocyte Ratio (Plr) may be superior to C-Reactive Protein (Crp) for predicting the occurrence of differentiated thyroid cancer

Ozmen Sevilay , Timur Ozge , Calik Ilknur , Altinkaynak Konca , Zipak Elif , Simsek Eda , Yildiz Faruk , Sevimli Hakan , Gozcu Hakan , Arslan Abdulmuttalip , Carlioglu Ayse

Aim: Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are prognostic markers of differentiated thyroid cancers. In our study we evaluated NLR, PLR and C-reactive protein for predicting the occurence of differentiated thyroid cancer. This is the first study that compares NLR and PLR to C-reactive protein indifferantiated thyroid cancer not only papillary cancer but also folliculer cancer.Materials and Method: This study includes 51 pa...