Searchable abstracts of presentations at key conferences in endocrinology

ea0056p497 | Diabetes therapy | ECE2018

A case with metformin overdose associated acidosis

Yilmaz Merve , Karatas Adnan , Kehribar Demet Yalcin

Introduction: Metformin-induced lactic acidosis (MALA) is one of the most important drug toxicities with high morbidity and mortality rates. Nonspecific symptoms such as nausea, vomiting, epigastric pain, hypotension, tachycardia, tachypnea, arrhythmia, renal insufficiency, coma and cardiac arrest can be seen. Here we are presenting a case with acidosis due to metformin overdose.Case: A 36-year-old female patient with a history of type 2 diabetes for thr...

ea0037ep252 | Calcium and Vitamin D metabolism | ECE2015

Comparison of the pre-operative and post-operative haemogram parameters of the patients with primary hyperparathyroidism

Tunc Ulku Aybuke , Demir Tevfik , Yilmaz Merve , Gedik Arzu

Anaemia prevalence is reported between 5 and 31.8% in patients with PHPT. Anaemia in PHPT shows correlations with serum calcium, PTH, alkaline phosphatase levels, severity of the bone disease and PHPT duration. In this study we compared pre-operative and post-operative haemogram parameters of patients with PHPT who received a parathyroidectomy at our department. We determined the prevelance of pre-operative anaemia, thrombocytopenia, neutropenia and observed if any of this par...

ea0037ep723 | Pituitary: clinical | ECE2015

Determinants of neutrophil/lymphocyte ratio in acromegaly patients

Yilmaz Merve , Gedik Arzu , Demir Tevfik , Cimrin Dilek , Comlekci Abdurrahman

Introduction: Neutrophil/lymphocyte ratio (NLR) is an indicative of the acute phase response. It is a significant indicator of the systemic inflammation, and considered as a poor prognosis indicator in various disease. We aimed to evaluate NLR and its determinants in acromegaly patients.Patients and methods: A retrospective chart review of 40 patients with acromegaly and 45 age and sex matched healthy individuals was performed. Patients with active infec...

ea0022p96 | Bone/Calcium | ECE2010

Hypoparathyroidism mimicking ankylosing spondylitis

Gedik Arzu , Yilmaz Merve , Eraydin Ayten , Gunes Mustafa , Eraslan Sevinc

Idiopathic hypoparathyroidism (IHP) is an uncommon disease in which soft tissue calcifications may be seen. We report a case with IHP with asymptomatic hypocalcemia and features of ankylosing spondylitis (AS).Case: A 58-year-old male patient was referred to our department due to incidentally discovered hypocalcemia when admitted with blurred speech, gait and posture abnormalities. He had had a generalized convulsion 19 years ago. On physical examination,...

ea0041ep178 | Calcium and Vitamin D metabolism | ECE2016

A Rare Case of Intracranial Calcification: Fahr Disease

Yilmaz Merve , Tanrivermis Asli , Kehribar Demet Yalcin , Akdemir Neslihan Unal , Karadas Adnan , Akyol Ozkan

Introduction: Fahr disease, is a rare pathology characterized by neuropsychiatric symptoms and bilateral symmetrical intracranial, especially basal ganglial calcifications. Although the exact etiology is not known, it is often associated with calcium and phosphorus metabolism disorders. We aim to present two brothers who presented with Fahr’s disease which is a rare condition.Case: Sixty-year-old male patient without a medical history of ilness was ...

ea0037ep231 | Calcium and Vitamin D metabolism | ECE2015

Is there a relationship between neutrophil/lymphocyte ratio and vitamin D levels in individuals over 65 years of age?

Yilmaz Merve , Gedik Arzu , Demir Tevfik , Eraydin Ayten , Cimrin Dilek , Comlekci Abdurrahman , Eraslan Sevinc

Introduction: Vitamin D deficiency may be an important predisposing factor for infections as well as autoimmune diseases in old individuals. Neutrophil/lymphocyte ratio (NLR), is a meaningful indicator of inflammation throughout the body. In this study we aimed to show, whether or not a relationship exists between vitamin D levels and NLR in patients older than 65 years.Materials and method: Data of 82 patients over 65 years of age was retrospectively ex...

ea0035p501 | Diabetes therapy | ECE2014

Is there a relationship between body composition and insulin regimen modality in type 1 diabetic patients?

Yilmaz Merve , Gedik Arzu , Yilmaz Simge , Bektas Belgin , Cimrin Dilek , Bayraktar Firat , Demir Tevfik

Introduction: Diabetes is characterized by an increase in abdominal fat. This results in a decrease in lean body mass and increase in insulin resistance. In this study, we aimed to evaluate the possible relationship between body composition and insulin regimen modality in type 1 diabetic patients.Materials and methods: Ninety-two type 1 diabetic patient followed in our institution were included in the study. Patients were classified into two groups accor...

ea0032p629 | Growth hormome IGF axis – basic | ECE2013

Determinants of carotid intima media thickness in acromegaly patients

Yilmaz Merve , Gedik Arzu , Basaloglu Can , Cimrin Dilek , Ellidokuz Hulya , Secil Mustafa , Comlekci Abdurrahman

Introduction: Acromegaly is a rare disease characterized by GH and IGF1 hypersecretion and increased cardiovascular mortality. Ultrasonographic measurement of carotid intima media thickness (CIMT) gives substantial information about early atherosclerosis. We aimed to evaluate CIMT and its determinants in a group of acromegaly patient.Patients and methods: Forty-four acromegaly patient and 43 age, sex and body mass index (BMI) matched healthy controls wer...

ea0032p904 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Clinical, hormonal and radiological characteristics of a group of primary empty sella patients

Gedik Arzu , Yilmaz Merve , Demir Tevfik , Bayraktar Firat , Men Suleyman , Eraslan Sevinc , Comlekci Abdurrahman

Background: Primary empty sella is an anatomical term defining the herniation of subarachnoid space within the sella turcica without an underlying factor such as pituitary tumor, surgery, irradiation or trauma.Patients and methods: We retrospectively evaluated clinical, hormonal and radiological data of the patients with primary empty sella syndrome followed in our institution between 2001 and 2012.Results: Ninety-four patients (80...

ea0032p912 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Prevalance of cancer in acromegaly patients; a single center data

Gedik Arzu , Yilmaz Merve , Demir Tevfik , Yener Serkan , Bayraktar Firat , Eraslan Sevinc , Comlekci Abdurrahman

Introduction: The growth promoting effects of GH and IGF1 has lead to increasing number of cancer surveillence studies in acromegaly so far. We herein aimed to present the prevalance of cancer in acromegaly patients followed in our institution.Patients and design: We retrospectively analyzed medical records of 151 patients with acromegaly (83 females) followed in our department from 2001 to 2012.Results: Overall, cancer was detecte...