Searchable abstracts of presentations at key conferences in endocrinology

ea0032p307 | Clinical case reports - Thyroid / Others | ECE2013

Prolonged ventilator dependence in myxedema coma: a case report and review of the literature

Cher Liu Yuan Gabriel , Jye Seow Cherng , Chew Daniel Ek Kwang

Introduction: Myxedema coma is a medical emergency and can be associated with respiratory failure. Intubated patients have been known to require persistent efforts in ventilator weaning, with one case reported to take 7 months before success.Case report: A 77-year-old gentleman with known primary hypothyroidism presented with chest infection. He had defaulted thyroxine for the past 6 months, relying instead on complementary health products. Thyroid funct...

ea0032p252 | Clinical case reports – Pituitary/Adrenal | ECE2013

Non-Hodgkin’s lymphoma presenting as anterior hypopituitarism

Lee Shang Ming Samuel , Abel Chen Weiliang , Gabriel Cher Liu Yuan , Lee Wei Feng , Seow Cherng Jye , Kon YC

Introduction: Panhypopituitarism is a known but rare presentation of lymphoproliferative disease. We describe a patient with newly diagnosed advanced diffuse large B-cell lymphoma who presented with anterior hypopituitarism and concomitant adrenal gland involvement.Case report: A 72 year-old Chinese woman presented with a few weeks’ duration of lethargy, weight loss and functional decline. A hormonal screen done at admission suggested central hypoth...

ea0032p260 | Clinical case reports – Pituitary/Adrenal | ECE2013

Therapeutic dilemmas in a young male patient with macroprolactinoma complicated by hypogonadism

Lee Wei Feng , Cher Liu Yuan Gabriel , Lee Shang Ming Samuel , Chen Weiliang Abel , Seow Cherng Jye , Hoi Wai Han

Introduction: Hypogonadism is known to persist after treatment of hyperprolactinemia, necessitating androgen therapy in young male patients. Aromatisation of testosterone to estradiol can result in tumor expansion. We report a patient with persistent hypogonadism post treatment of macroprolactinoma and discuss challenges involved in the management.Case report: A 51-year-old gentleman was admitted for streptococcal meningitis. Brain imaging revealed a pit...

ea0032p323 | Clinical case reports - Thyroid / Others | ECE2013

Androgen abuse complicated by polycythemia in a man with acquired immunodeficiency syndrome (AIDS)

Seow Cherng Jye , Chen Weiliang Abel , Lee Shang Ming Samuel , Gabriel Cher Liu Yuan , Lee Wei Feng

Introduction: Male hypogonadism secondary to AIDS is common and may present with non specific symptoms. Patients may self-diagnose hypogonadism and seek unauthorised androgen therapy. We report a male patient who developed polycythemia after receiving unauthorised sources of androgen therapy.Case report: A 42 years old man with AIDS diagnosed 10 years ago has repeatedly refused antiretroviral therapy. His most recent CD4 count was 314 cells/μl. His ...

ea0032p786 | Obesity | ECE2013

Rapid reversal of hyperglycemia despite modest weight loss in a patient post gastric bypass surgery: a case report and review of the literature

Weiliang Chen Abel , Shang Ming Lee Samuel , Feng Lee Wei , Liu Yuan Cher Gabriel , Jye Seow Cherng , Tar Khor Hong

Background: Bariatric surgery has been shown to decrease insulin requirements even before significant weight loss has occurred. We report a patient with marked improvement in glycemic control despite modest weight loss post bariatric surgery.Case presentation: A 47 years old Chinese man with obesity (weight 90 kg, BMI 31.2), hypertension, hyperlipidemia and type 2 diabetes mellitus diagnosed in 2005 is on follow up with our endocrine clinic. Despite comp...

ea0032p302 | Clinical case reports - Thyroid / Others | ECE2013

Hypercalcemia secondary to concomitant thyrotoxicosis and B cell lymphoma

Yuan Liu , Cher Gabriel , Lee Wei Feng , Chen Weiliang Abel , Lee Shang Ming Samuel , Jye Seow Cherng , Tan Alvin Wai Kit

Introduction: Mild hypercalcaemia can present in 10–15% of hyperthyroid patients. In contrast, its incidence in B cell lymphoma is considerably less (7–8%) but its levels are much higher. We report a patient with hypercalcemia secondary to both thyrotoxicosis and lymphoma.Case report: A 55 year-old lady presented with non specific symptoms of appetite loss and lower limb weakness. Comorbidities included hypertension, diabetes mellitus, hyperlip...

ea0032p310 | Clinical case reports - Thyroid / Others | ECE2013

Challenges in the management of hypogonadotropic hypogonadism

Seow Cherng Jye , Cher Liu Yuan Gabriel , Lee Shang Ming Samuel , Chen Weiliang Abel , Lee Wei Feng , Tan Alvin Wai Kit , Shakoor Shaikh Abdul Kader Kamaldeen Abdul

Introduction: One of the main challenges in the management of male hypogonadotropic hypogonadism (HH) is in the restoration of fertility. We describe 2 patients with HH and discuss the difficulties involved in their management.Case (1): A 23-year-old Chinese man presented with lack of secondary sexual characteristics. Examination revealed Tanner Stage 2 with descended testes measuring 6 ml bilaterally. Laboratory results: total testosterone (TT) <1 n...