Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1657 | Thyroid (non-cancer) | ICEECE2012

miRNA expression of the thyroid after goiter formation and involution using different iodine regimens

Mao J. , Chong W. , Shan Z. , Teng W.

Background: Thyroid damage is known to occur during experimental iodine-induced goiter. MicroRNAs (miRNAs) are a class of small non-coding RNAs regulating gene expression. Dysregulation of specific miRNAs can interfere with tissue homeostasis. The purpose of this study was to investigate the dynamic expression profiles of miRNAs during adequate or mild-excess iodine supplementation in the iodine-deficient thyroid.Methods: Hyperplastic goiter was induced ...