Endocrine Abstracts

We present a case of a 56-year-old male who reported to us with history of instability of gait since one year which was acute in onset and progressive, there was also history of hearing impairment and constipation since 3 years without improvement despite several symptomatic treatments. There was no history of weakness in any part of body, headache, vomiting, convulsions or alteration of sensorium. There was no history of trauma to the head, fever or drug intake. On examinatio...

Introduction: Pheochromocytoma is a rare tumor of chromaffin cells localized in the adrenal gland. It is responsible of secretion of catecholamines in a supra physiologic amount, leading to hypertension. Some patients may present with hypotension despite having high circulating levels of catecholamines. The challenge is to stabilize blood pressure by medication in cases with fluctuation of blood pressure.Case presentation: 49-year-old woman suffered from...

Introduction: The treatment of Graves’ disease is represented principally by anti-thyroid drugs, radioiodine ablation or thyroidectomy. Methimazole is the most used drug for the initial treatment. It is rare to encounter patients with resistant hyperthyroidism despite high doses of MMI.Case presentation: A 41-year-old woman was referred to our unit for resistant thyrotoxicosis. She had a confirmed Graves’ disease with positive serum Trab. Whils...

Introduction: Chronic excess of growth hormone is responsible for numerous cardiovascular, respiratory, metabolic and neoplastic complications, leading to significant morbidity and mortality. The aim of this study is to analyze the different cardiovascular manifestations and cardiovascular risk factors in acromegaly.Methods: A retrospective descriptive study including 44 patients hospitalized in the endocrinology department of University Hospital Mohamed...

Introduction: The COVID pandemic was a challenge in terms of physiopathology and therapeutics. Diabetics represent more than 40% of patients hospitalized for COVID. There was many new cases of diabetes declared during or after a COVID. The purpose of this report is to raise the link between Sars-Cov-2 infection and the appearance of glycemic disorders and new cases of diabetes.Case Presentation 1: A 28-years-old man who had a serious COVID-19 a month ago...

Introduction: Diabetic osteoarthropathy (D.O) commonly referred to as Charcot’s foot is a complication secondary to neuropathic and inflammatory osteolysis, occurring in a setting of old and/or poorly controlled diabetes. Its pathophysiology remains poorly understood and its diagnosis must be systematically evoked in the presence of any inflammatory sign that localised to the foot or ankle occurring on a background of diabetic neuropathy.Clinical ca...

Introduction: Sinonasal neuroendocrine carcinoma SNECs are a rare group of neoplasms that account for only 5% of all sinonasal malignancies. SNECs are categorized by their differentiation grade into well-, moderately- and poorly differentiated.Case report: We describe a classical case of SNEC with secondary orbital involvement in a 34-year-old male patient presented of the occurrence of a right epistaxis. First of all, the patient is smoking. The beginni...

Introduction: Pheochromocytoma is a rare cause of hypertension in pregnancy. Its prevalence ranges from 0.2% to 0.002% of cases of hypertension in pregnancy. Early diagnosis and appropriate management can reduce mortality and morbidity. Were report a case of pheochromocytoma diagnosed during pregnancy.Observation: 34-year-old diabetic patient, 29 weeks pregnant. Admitted for hypertensive peaks up to 170 mmHg of systolic, initially mistaken for pre-eclamp...

Introduction: Silent somatotroph pituitary adenomas are defined as pituitary adenomas with positive immunostaining for GH without signs of clinical or biochemical acromegaly. Silent somatotroph adenomas are rare and diagnosis is made post-operatively. Almost two-thirds are mixed GH-prolactin tumors. We report the case of a non-functioning macroadenoma coexpressing prolactin and GH.Observation: A 37-year-old man presented with headache and progressive vis...