Searchable abstracts of presentations at key conferences in endocrinology

ea0063p753 | Thyroid 2 | ECE2019

Falsely high serum calcitonin levels

Stojkovic Mirjana , Beleslin Biljana , Ciric Jasmina , Stojanovic Milos , Zarkovic Milos

Calcitonin is a polypeptide hormone synthesized and secreted by the parafollicular cells of the thyroid gland, and has been considered as a good marker for medullary thyroid carcinoma. But several physiologic and pathologic conditions other than medullary thyroid carcinoma have been associated with increased levels of calcitonin. A 39-year old woman was admitted to our hospital for further testing due to high calcitonin level (467 ng/L) measured by immunochemiluminometric assa...

ea0056p1059 | Thyroid (non-cancer) | ECE2018

Metabolic profile in patients with subclinical hypothyroidism

Stojkovic Mirjana , Savic Slavica , Ciric Jasmina , Nedeljkovic-Beleslin Biljana , Stojanovic Milos , Zarkovic Milos

Background: Thyroid function regulates a wide array of metabolic parameters and significantly affects lipoprotein metabolism. Subclinical hypothyroidism (SCH) is the most common thyroid disorder, with a prevalence up to 10% in adult populations. Subclinical hypothyroidism is defined as mild elevation in thyroid stimulating hormones (TSH) in presence of normal free thyroxine (fT4) and free triiodothyronine (fT3). This mild elevation of serum TSH is caused by a minor initial dec...

ea0037ep937 | Thyroid (non-cancer) | ECE2015

Side effects of steroid therapy in Graves' orbitopathy: comparison of two different protocols: parenteral vs combined parenteral and oral

Beleslin Biljana , Ciric Jasmina , Stojkovic Mirjana , Savic Slavica , Ciric Slavica , Lalic Tijana , Nisic Tanja , Stojanovic Milos , Zarkovic Milos

Introduction: Glucocorticoids (GCs) are the treatment of choice for moderate-to-severe and active Graves’ orbitopathy (GO), but optimal treatment is still undefined as serious side effects are great concern of GC therapy. The aim of the present study was to evaluate tolerability and safety of two different treatment protocols.Methods: Consecutive patients were divided according to the protocol of GC therapy into two groups: combined intravenous and ...

ea0022p48 | Adrenal | ECE2010

Combined primary aldosteronism and preclinical Cushing's syndrome due to a large adrenocortical adenoma

Ciric Jasmina , Beleslin Biljana , Stojkovic Mirjana , Trbojevic Bozo , Zarkovic Milos

The rarest causes of primary aldosteronism are aldosterone producing carcinoma, ectopic aldosterone secretion and familial aldosteronism. There are also few cases reported of aldosterone and cortisol tumor cosecretion. We present a 38-year-old woman admitted to our hospital because of resistant hypertension, large adrenal tumor and hypokalemia. At age 32 hypertension was diagnosed, but routine laboratory and abdominal ultrasound examination were normal. Few months before admis...

ea0049ep1261 | Thyroid (non-cancer) | ECE2017

Therapeutic options in severe thyrotoxicosis with malabsorption

Stojkovic Mirjana , Savic Slavica , Nedeljkovic-Beleslin Biljana , Ciric Jasmina , Nisic Tanja , Zarkovic Milos

Abstract: A 55-year-old woman was admitted to our hospital due to severe hyperthyreosis. She started to feel symptoms of hyper-metabolism four months prior to hospitalization. At that time she was admitted in regional hospital and had gastroenterological examination because of diarrhea. Crohn’s disease was diagnosed and therapy started. At the same time, thyrosupressive therapy started. She had a history of hyperthyreosis thirteen years ago, duodenal hemorrhage ulcer, hyp...

ea0070ep23 | Adrenal and Cardiovascular Endocrinology | ECE2020

Pseudoglandular myxoid adrenal cortical adenoma and secondary hyperaldosteronism

Stojkovic Mirjana , Stojanovic Milos , Nedeljkovic-Beleslin Biljana , Ciric Jasmina , Miletic Marija , Zarkovic Milos

Myxoid adrenocortical adenoma is a rare adenoma originated from adrenal cortex. A 51 years old male patient was admitted to our hospital due to hypertension and hypokalemia. He has a long history of nonregulated hypertension despite multiple antihypertensive medications. Hypokalemia was detected in last two years with potassium levels around 3.0 mmol/l on high supplementation dose up to 10–16 g of KCl/day. He is obese in the past 10 years. His family history was positive...

ea0032p290 | Clinical case reports - Thyroid / Others | ECE2013

Neurogenic hypertension as a case report

Nisic Tanja , Stojkovic Mira , Stojanovic Milos , Ciric Jasmina , Beleslin Biljana , Lalic Tiana , Zarkovic Milos , Trbojevic Bozo

Introduction: Neurogenic hypertension is associated with unilateral neurovascular compression of the brainstem and cranial nerves V, IX-X, VII, VIII. Causes may include nerve injury, vascular compression, tumors. Symptomatology seems hyperactive dysfunction syndrome of the cranial nerves. In the clinical picture, it can be seen trigeminal neuralgia, vertigo, tinnitus, hemifacial spasm, and in some cases hypertension.Case report: Female patient, 45 years ...

ea0032p985 | Thyroid (non-cancer) | ECE2013

Efficacy and safety of combined parenenteral and oral steroid therapy in Graves' orbitopathy

Beleslin Biljana , Ciric Jasmina , Zarkovic Milos , Knezevic Miroslav , Stojkovic Mirjana , Lalic Tijana , Nisic Tanja , Trbojevic Boza

Introduction: Glucocorticoids (GC) are the first line treatment for moderate-to-severe and active Graves’ orbitopathy (GO), but optimal treatment is still undefined. The aim of the present study was to analyze the efficacy and tolerability of combined parenteral GC pulse therapy followed by oral GC in the interpulse period.Methods: The study includes 50 patients (48±10 years; 37 females) with untreated, active and moderate-to-severe GO. Patient...

ea0032p1051 | Thyroid (non-cancer) | ECE2013

The influence of thyroid hormones on the variability of blood pressure

Nisic Tanja , Stojanovic Milos , Stojkovic Mirjana , Beleslin Biljana , Ciric Jasmina , Lalic Tijana , Trbovic Bozo , Zarkovic Milos

Introduction: Changes in thyroid function have significant impact on the cardiovascular system.Methods: In a group of 37 subjects the level of thyroid hormones FT4, FT3, and TSH were measured. Then carried out short-term analysis for 30 min measureing variability of blood pressure with non-invasive TASK FORCE monitor. Registered data were analyzed by spectral analysis of variability. Statistical analysis were done by Pearson correla...

ea0022p793 | Thyroid | ECE2010

Differences in Graves' orbitopathy between hyperthyroid and hypothyroid/euthyroid patients

Beleslin Biljana , Ciric Jasmina , Zarkovic Milos , Stojkovic Mirjana , Ciric Slavica , Knezevic Miroslav , Trbojevic Bozo

Aim: The aim of this study was to compare clinical symptoms and TSH receptor antibodies (TRAb) in Graves orbitopathy (GO) in hyperthyroid patients to those patients with primarily hypothyroid and euthyroid status.Methods: Study group consisted of 54 primarily hyperthyroid (39 female, 14 male, 47±9 years) and 8 primarily hypothyroid and euthyroid patients (5 female, 3 male, 46±14 years). Clinical symptoms and TRAb were assessed. Assessment of th...