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ea0099rc1.7 | Rapid Communications 1: Reproductive and Developmental Endocrinology | ECE2024

Characterisation of the daily rhythm of salivary androgens in healthy women and in women with polycystic ovary syndrome by liquid chromatography-tandem mass spectrometry

Rotolo Laura , Gambineri Alessandra , Bissi Valentina , Zauli Francesca , Galante Greta , Cecchetti Carolina , Dionese Paola , Belardinelli Elisabetta , Solmi Beatrice , Pagotto Uberto , Fanelli Flaminia

Background: PCOS is characterised by increased production of ovarian and adrenal androgens. Obesity is closely connected to excess androgens and to the disruption of hormone circadian rhythmicity. To date, it is not clear whether hyperandrogenism in PCOS, complicated or not by obesity, is associated with androgen rhythm dysregulation.Aim: To investigate androgen diurnal rhythmicity and overall daily androgen exposure by measuring testosterone(T), androst...

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Characterisation of the daily rhythm of salivary androgens in healthy women and in women with polycystic ovary syndrome by liquid chromatography-tandem mass spectrometry

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