Searchable abstracts of presentations at key conferences in endocrinology

ea0016p623 | Reproduction | ECE2008

Pathogenesis of the congenital forms of hypogonadotropic hypogonadism

Zektser Vita , Ilovayskaya Irena , Zakcharova Ekaterina , Keda Julia , Melnichenko Galina

In purpose to elucidate pathogenetic mechanisms of congenital forms of hypogonadotropic hypogonadism we have examined 25 women with idiopathic hypogonadotropic hypogonadism (IHH), mean age 26 years and 7 months (group 1). All patients had amenorrhea, little breast development (Tanner 2–3), absence or little axillery and pubic hair, infantile uterus and decreased ovary volume. There were no pathological changes during MRI-investigation. Twenty healthy women were included i...

ea0014p256 | (1) | ECE2007

HRT in treatment of dislipidemia in women with hypogonadotropic hypogonadism

Zektser Vita , Ilovayskaya Irena , Iliyn Aleksandr , Goncharov Nikolay , Melnichenko Galina

Hypoestrogenemia is associated with dislipidemia and is an independent risk factor for cardiovascular diseases in postmenopausal women. However, there is a cohort of young women with gonadal steroid deficit caused by the disorders of central regulation. Twenty women with hypogonadotropic hypogonadism (HH) were included in group 1. (median age - 29 years and 3 months, median duration of amenorhea - 5 years 3 months, mean BMI - 24.6±6.05 kg/cm2. Women were examined before a...

ea0022p484 | Female reproduction | ECE2010

Metabolic changes associated with hypogonadotropic hypogonadism in women of reproductive age and effect of HRT

Ilovayskaya Irena , Zektser Vita , Iljin Alexandr , Goncharov Nikolay , Melnichenko Galina , Dedov Ivan

We examined 56 normoprolactinemic women of reproductive age (18–45 y.o.) with isolated hypogonadotropic hypogonadism (group 1) initially and on treatment with 2 mg of 17β-estradiol and 10 mg of dydrogesterone in sequenced manner (HRT), duration of HRT was from 18 to 42 (median 36) months; 45 healthy women (20–38 y.o.) were included in control group 2.Initially hypercholesterolemia was observed in 50% of cases in group 1 and 6.6% in group 2...