ea0063p1034 | Interdisciplinary Endocrinology 2 | ECE2019
Fanelli Flaminia
, Mezzullo Marco
, Temchenko Anastasia
, Cantu Marco
, Lindner Johanna M
, Peitzsch Mirko
, Hawley James M
, Bruce Stephen
, Zelzer Sieglinde
, Herrmann Markus
, Heijboer Annemieke C
, Van den Ouweland Jody
, Eisenhofer Graeme
, Keevil Brian G
, Rauh Manfred
, Vogeser Michael
, Pagotto Uberto
Background: LC-MS/MS is replacing immunoassays for serum steroid measurement in clinical labs worldwide. The intrinsic high specificity of LC-MS/MS is supposed to guarantee accurate quantitation, however, differences in pre-analytical and analytical procedures, and overall performance may influence the result. A few studies so far investigated the reproducibility among different LC-MS/MS assays for sex steroids. No data are available for adrenal steroids.<p class="abstext"...