Searchable abstracts of presentations at key conferences in endocrinology

ea0063p248 | Pituitary and Neuroendocrinology 1 | ECE2019

Study of relationship between levels of kisspeptin and neurokinin B and markers of calcium-phosphate metabolism and water-electrolyte balance in patients with neuroendocrine disorders

Pigarova Ekaterina , Vorotnikova Svetlana , Zhukov Artem , Dzeranova Larisa , Petrushkina Alexandra , Nikankina Larisa

Objective: To study the effect of neurohormones kisspeptin and neurokinin B on the indices of calcium-phosphate and electrolyte metabolism in patients with neuroendocrine pathology.Material and Methods: Eighty-two female patients were included in this pilot study divided into 2 groups: ‘Cushing’s disease’ group (n=51) and ‘Acromegaly’ group (n=31). Median age was 33 years [27; 38] in ‘Cushing’s disease...

ea0063p1069 | Pituitary and Neuroendocrinology 3 | ECE2019

Apelin, copeptin, aldosterone and renin in patients with hyponatremia after transnasal surgery for pituitary tumors

Pigarova Ekaterina , Zhukov Artem , Dzeranova Larisa , Malysheva Natalia , Nikankina Larisa , Melnichenko Galina , Dedov Ivan

Introduction: Hyponatremia after transnasal neurosurgery for pituitary adenomas is a serious and not so rare complication. It often occurs in a delayed manner after patient’s discharge and is a major cause of readmission. The pathogenesis of postneurosurgical hyponatremia is not clear yet.Aims: To study the role of posterior pituitary hormones (antidiuretic hormone (ADH) and apelin) and reaction of renin-aldosterone system (RAS) at hyponatremia mani...

ea0063p82 | Calcium and Bone 1 | ECE2019

A case report of tumor-induced osteomalacia

Zhukov Artem , Pigarova Ekaterina , Petrushkina Alexandra , Rozhinskaya Liudmila , Beltsevich Dmitry , Slashuk Konstantin , Rumyantsev Pavel , Kogan Evgeniya , Osmanov Yusif , Melnichenko Galina

Objective: Tumor-induced osteomalacia is a rare paraneoplastic syndrome in which fibroblast growth factor 23 (FGF-23) hyperproduction by tumor causes renal phosphate wasting, severe hypophosphatemia and osteomalacia. Localization of the tumor can be a major diagnostic challenge.Material and methods: We present a clinical case concerning a 62-year old woman previously diagnosed with hypophosphatemic osteomalacia, with a slight improvement of clinical and ...