Endocrine Abstracts

Purpose: Adrenal vein sampling (AVS) is the gold standard method for subtyping primary aldosteronism (PA). A certain number of PA patients had unilateral successful AVS, concomitant autonomous cortisol secretion or indeterminate lateralization index (LI 2.5–4), which made correct interpretation of AVS data impossible. The aim of our study was to determine whether absolute aldosterone concentration can predict the subtype of PA in patients with inconclusive AVS data.<p...

Objective: Patients with Cushing syndrome (CS) have impaired health-related quality of life (HRQoL) before and after surgery. The data on the optimal hydrocortisone dose after surgical cure of CS is scarce. Therefore, we investigated the influence of hydrocortisone dose on HRQoL after surgical treatment of CS. We hypothesized that patients who receive higher hydrocortisone doses after surgery would have better HRQoL and fewer cortisol withdrawal symptoms.<p class="abstext"...

Objective: This study aimed to investigate the diagnostic performance of 18F-choline PET/CT in patients with negative or inconclusive results of 99mTc-sestamibi SPECT/CT in locating hyperfunctioning parathyroid tissue in primary hyperparathyroidism patients.Methods: We conducted a retrospective study involving patients who were operated on due to primary hyperparathyroidism from April 2019 to March 2022. The analysis focused on pati...

Background: Systematic or randomised studies on the natural course of non-functioning pituitary macroadenomas after surgery (NFPA) are lacking.Objectives: This study aimed to evaluate the long-term outcomes of residual NFPA following pituitary surgery.Methods: In this retrospective study, we included 130 patients with NPFA who underwent pituitary surgery between 2005 and 2018 at University Hospital Centre Zagreb. The median age of ...

Introduction: Adrenocortical carcinoma (ACC)is a rare disease with an unfavourable prognosis. Complete surgical resection of the tumour provides the only chance for long-term cure. The aim of this study was to compare long term outcomes in patients with ACC referred to surgery in an expert adrenal centre (EC) versus nonspecialised centres (NSC).Materials and methods: This retrospective study included 48 patients with ACC, ENSAT stage I-III. All of study ...