Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1763 | Thyroid cancer | ICEECE2012

Ultrasound-guided fine-needle aspiration biopsy (US-FNAB) of thyroid nodules: effects of the operator’s experience on adequacy of sampling: the MoCyThy (Modena’s Cytology of the Thyroid) DATABASE

Vezzani S , Ansaloni A , Zirilli L , Cioni K , Diazzi C , Simoni M , Madeo B , Rochira V

Introduction: Thyroid FNAB is the gold standard to discriminate malignant from benign thyroid nodules. However, inadequate cytology ranges from 1 to 20% (up to 33.6%) in different settings and could depend on several factors, including the operator’s skills.Aim: To evaluate the effect of operator’s experience on US-FNAB diagnostic adequacy we reviewed 7029 US-FNABs performed from January 2006 to March 2009.Materials and M...

ea0029p1764 | Thyroid cancer | ICEECE2012

Value of repeated US-guided fine-needle aspirations (US-FNAB) in the follow-up of thyroid nodules: the MoCyThy (Modena’s Cytology of the Thyroid) DATABASE

Ansaloni A. , Belli S. , Vezzani S. , Granata A. , Zirilli L. , Cioni K. , Carani C. , Madeo B. , Rochira V.

Introduction: There is no consensus about the usefulness of repeating the US-FNAB during the follow-up of nodules when a benign (Thy2) or indeterminate (Thy3) report is obtained at first US-FNAB.Aim of the study: To investigate the clinical value of repeating US-FNAB after a previous adequate Thy2 or Thy3 US-FNAB.Methods: We reviewed the US-FNABs performed from 2006 to 2009. All clinical data of the patients were collected and anal...

ea0026p153 | Male reproduction | ECE2011

Lower serum testosterone and estradiol (E2) in adult men with unfused epiphyses due to unrecognized and untreated congenital hypogonadotropic hypogonadism: evidence for an E2 threshold for bone maturation in men

Rochira V , Balestrieri A , Zirilli L , Madeo B , Sgarbi I , Luberto A , Carani C

Introduction: At puberty, the raise of serum estradiol (E2) (after testosterone conversion) is needed to fuse ephiphyses and to complete bone maturation in boys. Owing to severe hypogonadism and very low circulating testosterone, adult men with congenital hypogonadotropic hypogonadism (CHH) may present with unfused epiphyses and continuing linear growth if androgen deficiency is unrecognized and untreated. In order to establish the minimal amount of sex steroids nee...

ea0083rdo4 | Reproductive and Developmental Endocrinology | EYES2022

Comparison of eunuchoid skeletal proportions in male hypogonadism between men with congenital hypogonadotropic hypogonadism (CHH) and Klinefelter Syndrome (KS)

A. Bellelli , S. De Vincentis , R. Corleto , L Zirilli , E Santamaria , A Granata , V. Rochira

Background: Patients with CHH and KS share eunuchoid body proportions of skeleton compared to normal male subjects. On the contrary, testosterone levels at puberty are lower in CHH patients compared to KS patients.Aim: To compare anthropometric measurements of adult male CHH vs KS patients.Methods: A prospective, cross-sectional, observational study was conducted. CHH patients were subdivided into 2 subgroups according to the timin...

ea0029p1768 | Thyroid cancer | ICEECE2012

Nursing assistance increases the efficiency of ultrasound-guided fine-needle aspiration biopsy (US-FNAB) in the management of thyroid nodules: the MoCyThy (Modena's Cytology of the Thyroid) DATABASE

Belli S. , Carani C. , Ansaloni A. , Cioni K. , Zirilli L. , Velasco M. , Simoni M. , Madeo B. , Rochira V.

Introduction: US-FNAB is the most cost/effective and accurate diagnostic procedure for the evaluation of thyroid nodules. In the clinic, the nursing assistance is not always available for the US-FNAB procedure in all endocrinological centers and its value remains to be established.Aim of the Study: To demonstrate the role of nursing assistance in US-FNAB procedures in improving the efficiency of this procedure.Methods: All clinical...

ea0026p148 | Male reproduction | ECE2011

Testosterone changes over time in men with human immunodeficiency virus infection: preliminary results

Brigante G , Santi D , Zirilli L , Diazzi C , Orlando G , Gnarini V , Carani C , Guaraldi G , Rochira V

Introduction: Male hypogonadism is very frequent in men treated with highly active anti-retroviral therapy (HAART) for Human Immunodeficiency Virus-1 (HIV-1) infection, reaching a prevalence of about 20%. Literature data regarding the time course of serum total testosterone (T) levels in these patients are lacking.Aim of the study: To evaluate changes of T levels over time in HIV-positive men with an initial finding of low T (<300 ng/dl).<p class...

ea0026p227 | Pituitary | ECE2011

Pituitary function in type 2 diabetic men with good or poor glycaemic control

Scaltriti S , Madeo B , Bertolini M , Romano S , Zirilli L , Cavani E R , Balestrieri A , Carani C , Rochira V

Introduction: Several data suggest that male hypogonadism occurs frequently in men with type 2 diabetes mellitus (T2DM) but underlying pathophysiological mechanism remains partially unknown. In order to investigate the short term effect of hyperglycaemic state on hypothalamic–pituitary–gonadal axis we prospectively studied 18 men with T2DM younger than 55 years at the time of first diagnosis of T2DM. We compared men with HbA1c≥9.0% with men with HbA1c≤9.0...

ea0029p1822 | Thyroid cancer | ICEECE2012

Prevalence of differentiated thyroid cancer is relevant in patiens with familial adenomatous polyposis: a case-control prospective study

Diazzi C. , Benatti P. , Zirilli L. , Gnarini V. , Madeo B. , Romano S. , Rossi G. , Carani C. , Ponz de Leon M. , Roncucci L. , Rochira V.

Introduction: Familial adenomatous polyposis (FAP) is a dominantly inherited disease characterized by colorectal adenomas, extracolonic gastrointestinal manifestations and extraintestinal diseases. Among them, differentiated thyroid cancer (DTC) is considered very frequent with an approximately risk 160 times higher than in general population, and with a prevalence of the cribriform-morular variant. As this esteem comes from scattered data, we evaluated in a prospective contro...