Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep230 | Bone and Calcium | ECE2020

Vertebral fractures in patients with castration-resistant prostate cancer undergoing treatment with Radium-223: A longitudinal study in the real-life clinical practice.

Mazziotti Gherardo , Rodari Marcello , Pepe Giovanna , Gelardi Fabrizia , Zucali Paolo , Chiti Arturo

Radium-223 was associated with high incidence of non-vertebral fractures in patients with castration-resistant prostate cancer (CRPC). The determinants of this effect are unknown and it is still unclear whether Radium-223 may induce skeletal fragility regardless of other therapies of CRPC. We aimed at evaluating the incidence and determinants of vertebral fractures (VFs), i.e. the hallmark of skeletal fragility, in CRCP patients undergoing Radium-223 therapy in the real-life c...

ea0081p305 | Calcium and Bone | ECE2022

Reliability of who fracture risk assessment tool (frax) and bone mineral density in predicting fractures in cancer patients under hormone deprivation therapies: a real-world clinical study

Vena Walter , Piccini Sara , Pedersini Rebecca , Carrone Flaminia , Cosentini Deborah , Zucali Paolo , Torrisi Rosalba , Brunetti Alessandro , Pigni Stella , Maroldi Roberto , Balzarini Luca , Lania Andrea Gerardo , Berruti Alfredo , Berruti Gherardo

Background: Skeletal fragility is an important clinical issue in women with early-stage breast cancer and men with non-metastatic prostate cancer under hormonal hormone deprivation therapies (HDTs). Vertebral fractures (VFs) have been reported in a remarkable number of subjects exposed to HDT especially when the diagnosis of fractures is performed by a radiological and morphometric approach. Notably, prediction of fractures in this clinical setting is a challenge and determina...