Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep175 | Reproduction, endocrine disruptors and signalling | ECE2015

Endocrine disorders in women with Turner syndrome

Zwolak Agnieszka , Dabrowska Anna , Tarach Jerzy

Introduction: Turner syndrome (TS) is the most common chromosomal abnormality in women. It occurs in 1/2500 to 1/3000 live-born females and results from a total or partial absence of the X chromosome. The clinical manifestations are diverse and TS is accompanied by multiple medical problems.Methods: We analysed retrospectively six cases of women with TS aged 20–66 years, treated at Endocrinology Department between 2003 and 2014, to describe endocrin...

ea0037ep1079 | Thyroid (non-cancer) | ECE2015

Multiple disease associations in autoimmune polyglandular syndromes

Dabrowska Anna , Zwolak Agnieszka , Tarach Jerzy

Introduction: Autoimmune polyglandular syndromes (APS) are a heterogeneous group of disorders characterised by autoimmune activity against endocrine and non-endocrine organs. APS type depends on the combination of the diseases (APS1, APS2, and APS3).Methods: The study was conducted in 89 patients (70F and 19M) with APS aged mean 50.00±14.80 years, treated at Endocrinology Department between 2003 and 2015. We analysed clinical manifestations, results...

ea0037ep1101 | Endocrine tumours | ECE2015

Von Hippel–Lindau disease: report of two cases

Dabrowska Anna , Tarach Jerzy , Zwolak Agnieszka

Introduction: Von Hippel–Lindau (VHL) disease is a rare autosomal dominant syndrome (1/36 000 live births) with highly penetrance that predisposes to the development of benign and malignant, highly vascularised tumours in many organs.Case reports: Two women with VHL, without family history of VHL, were admitted to Department of Endocrinology for checkups. The diagnosis was made based on genetic tests.Patient A: A 53-year-old w...

ea0035p283 | Clinical case reports Thyroid/Others | ECE2014

Primary hyperparathyroidism due to parathyroid carcinoma: case report

Zwolak Agnieszka , Dabrowska Anna , Tarach Jerzy

Introduction: About 1% of primary hyperparathyroidism is due to parathyroid carcinoma. The affected gland is often indistinguishable from atypical adenoma. The proper diagnosis is usually made when the disease recurs or metastases are present and then is connected with poor prognosis.Case report: A 49-year-old man, after resection of parathyroid adenoma (postoperatively with normalization PTH concentrations and hungry bone syndrome), with limbs’ fra...

ea0037ep472 | Diabetes (complications & therapy) | ECE2015

Is diabetes an independent risk factor of perioperative complications after abdominal gynecologic interventions?

Swirska Joanna , Matyjaszek-Matuszek Beata , Czuczwar Piotr , Zwolak Agnieszka

Purpose: We sought to determine if in the group of patients who underwent gynecologic abdominal interventions diabetes was an independent risk factor of perioperative complications.Material and methods: The study group included 62 women from both the diabetic and the control group who underwent elective gynecologic laparotomies such as hysterectomy or adnexectomy. The patients from diabetic group were pair-matched with patients without diabetes based on ...

ea0037ep736 | Pituitary: clinical | ECE2015

Persistent hyponatremia in patient with acromegaly, congestive heart failure and diabetes insipidus

Kurowska Maria , Malicka Joanna , Zwolak Agnieszka , Tarach Jerzy S

Introduction: Increased production of vasopressin plays a key role in the development of fluid retention and hyponatremia in patients with decompensated heart failure. Antidiuretic hormone deficiency in the course of diabetes insipidus leads to the loss of water, dehydration and hypernatremia. The aim of the study was to present difficulties in successful treatment of hyponatremia in a patient with cardiomyopathy and heart failure, receiving desmopressin because of postoperati...

ea0037ep756 | Pituitary: clinical | ECE2015

Sheehan's syndrome: a rare disease with typical symptoms

Dabrowska Anna , Tarach Jerzy , Zwolak Agnieszka , Oszywa-Chabros Anna

Introduction: The enlarged pituitary gland of pregnancy is susceptible to any compromise to its blood supply. Sheehan’s syndrome (SS) occurs as a result of post-partum pituitary infarction or haemorrhage and usually leads to hypopituitarism. It can be fatal but clinical manifestations may change from one patient to another and symptoms may not occur for many years.Methods: We analysed retrospectively five cases of women with SS aged 26&#150...

ea0037ep1092 | Endocrine tumours | ECE2015

Analysis of current indications to bilateral adrenalectomy

Kurowska Maria , Malicka Joanna , Zwolak Agnieszka , Tarach Jerzy S

Introduction: Bilateral adrenalectomy (BA) is rarely applied as a therapeutic procedure. It serves as a life-saving treatment in patients with persistent Cushing’s disease after an ineffective pituitary surgery or in ectopic ACTH production. Other indications for BA are: bilateral adrenocortical adenomas, congenital adrenal hyperplasia and bilateral phaeochromocytoma in patients with hereditary paraganglioma-phaeochromocytoma (PPS/PGL) syndromes. It is also a procedure of...

ea0037ep1153 | Clinical Cases–Pituitary/Adrenal | ECE2015

Recurrent hyponatremia in woman with undiagnosed postpartum pituitary insufficiency

Kurowska Maria , Malicka Joanna , Zwolak Agnieszka , Tarach Jerzy S

Introduction: Hyponatremia occurs in 33–69% of women with postpartum pituitary necrosis. The aim of the study was to present a patient in whom recurrent hyponatremia was one of the dominant symptoms of postpartum anterior pituitary hormones deficiency.A case report: 55-year-old woman with a diagnosis of Sheehan syndrome established 19 years after the last labor complicated by massive bleeding due to uterine atonia. The first symptoms of pituitary in...

ea0035p556 | Endocrine tumours and neoplasia | ECE2014

Catecholamin crisis as a first manifestation of multiple endocrine neoplasia type 2A

Zwolak Agnieszka , Rudzki Grzegorz , Swirska Joanna , Tarach Jerzy

Introduction: Multiple endocrine neoplasia type 2A (MEN2A) is a multi-glandular autosomal dominant genetic disorder which, most typically, includes medullary carcinoma of the thyroid, pheochromocytoma and primary hyperparathyroidism. The authors present a case study of a young man in whom cardiogenic shock was the first manifestation of pheochromocytoma and MEN2A.Case report: A 30-year-old man without a past history of hypertension or any other chronic m...