Searchable abstracts of presentations at key conferences in endocrinology

ea0081p201 | Thyroid | ECE2022

Indications and extended follow-up of radiofrequency ablation for treatment of hyperthyroidism caused by solitary autonomous functioning thyroid nodules

van der Meeren Manon , Joosten Frank , de Boer Hans , Deden Laura , J.G. Oyen Wim

Background: Hyperthyroidism caused by autonomous functioning thyroid nodules (ATN) is usually treated with I-131. Recently, radiofrequency ablation (RFA) has emerged as a promising alternative but it is not yet incorporated in guidelines.Aims: Assessment of efficacy of RFA treatment in patients with hyperthyroidism caused by ATN and factors that may affect treatment success.Methods: Retrospective analysis of patients treated for hy...

ea0022p95 | Bone/Calcium | ECE2010

Cross-validated calculation procedure to assess the cholecalciferol loading dose for rapid correction of vitamin D deficiency

van Groningen Lenneke , van Sorge Adriaan , Telting Darryl , Giessen Astrid , de Boer Hans

Introduction: Vitamin D deficiency is very common in Northern Europe. Recently, we developed an equation to calculate the vitamin D deficit, based on the serum 25-OH vitamin D3 (25OHD3) level and body weight: vitamin D deficit (IU)=40×(75−serum 25OHD3)×body weight. The calculated deficit gives the amount of cholecalciferol that is required to raise the serum 25OHD3 level to the target of 75 nmol/l.<p class="abstex...

ea0020p250 | Bone/Calcium | ECE2009

Colecalciferol loading dose guideline for vitamin D deficient adults

van Groningen Lenneke , van Sorge Adriaan , Telting Darryl , Giesen Astrid , de Boer Hans

Introduction: Severe vitamin D deficiency is very common in northern Europe. It is not limited to the elderly, but occurs in a large variety of subjects. Colecalciferol dosing guidelines for rapid correction of vitamin D deficiency are not available.Objective: To assess the optimal Colecalciferol dose regimen, based on body weight, for rapid correction of vitamin D deficiency, in a variety of subjects.Materials and methods: One hun...

ea0020p444 | Obesity and Metabolism | ECE2009

Letrozole normalizes serum testosterone and reduces body weight in morbidly obese men with obesity-related hypogonadotropic hypogonadism

Loves Sandra , de Jong Jos , van Sorge Adriaan , Telting Darryl , de Boer Hans

Introduction: Hypogonadotropic hypogonadism is frequently observed in morbidly obese men, due to aromatase-dependent conversion of androgens to estrogens in adipocytes. The clinical impact of this sex hormone imbalance is not known.Aim: To evaluate the clinical effects of aromatase inhibition in obesity-related hypogonadotropic hypogonadism.Methods: Double-blind, placebo-controlled trial for 6 months in severely obese men (BMI &#62...