ea0038p300 | Pituitary | SFEBES2015
de Oliveira Andrade Matheus
, Soare Dan Sebastian
, Radian Serban
, Korbonits Marta
Background: AIP mutations cause sporadic and familial pituitary adenomas, but establishing the pathogenic role of missense AIP variants with unknown significance is difficult. The AIP interaction partner AHR a xenobiotic-activated transcription factor regulates transcription of xenobiotic-metabolising enzymes, mediates xenobiotic toxicity, and has been implicated in tumorigenesis.Aim: To describe the effect of AIP...