ea0099p116 | Pituitary and Neuroendocrinology | ECE2024
van der Hoeven Loren
, Slagboom Tessa
, Malekzadeh Arjan
, Hoogmoed Jantien
, Drent Madeleine
, Aronica Eleonora
, Jan Stenvers Dirk
, Pereira Alberto
Background: In 2017, the World Health Organization (WHO) adjusted the histopathological classification of pituitary adenomas (PAs) by including pituitary cell lineage specific transcription factors (TFs), elucidating a continuous spectrum between true null cell (NCA), silent, clinically silent, and functioning adenomas. The definitions of non-functioning (silent) gonadotroph, corticotroph, somatolactotroph and thyrotroph adenomas were previously reserved for immunohistochemica...