Endocrine Abstracts

Introduction: Maternal obesity is associated with an increased risk of gestational diabetes, large for gestational age (LGA) newborns, preterm delivery, congenital malformations, and fetal death. On the other hand, bariatric surgery before pregnancy is associated with a reduction of obesity-associated complications, but also with an increased risk of small for gestational age (SGA) newborns, fetal growth restriction and micronutrient deficiencies during pregnancy.<p class=...

Introduction: Obese patients are at an increased risk of develop nonalcoholic fatty liver disease. Evidence supports that bariatric surgery might have an important impact on hepatic profile in obese adults. Literature suggests that bariatric surgery in adolescents might decrease the prevalence of some comorbidities, but information about its impact on liver profile and steatosis and fibrosis risk remains scarce.Aim: To evaluate the impact of bariatric su...

Introduction: Obesity is a complex multifactorial disease and its prevalence in pediatric age has increased. Obesity prejudices the individual metabolic profile due to the adipotoxicity involved in this condition. Bariatric surgery improves the weight of obese patients along with metabolic comorbidities, being today one of the most effective treatments for obesity. Time of exposure to adipotoxicity appears to be an important risk factor for the development of metabolic complic...

Introduction: Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome with high mortality, for which there are few disease modifying therapeutics. Thyroid axis dysfunction is common in heart failure (HF) and may contribute to the pathogenesis of HFpEF. However, the association of thyroid hormones (TH) with the clinical status of HFpEF patients and their prognostic impact in this syndrome are not clear. Methods: We evaluated 93 parti...

Introduction: Non-alcoholic fatty liver disease (NAFLD) and Heart Failure with Preserved Ejection Fraction (HFpEF) are two syndromes with increasing clinical relevance, mainly due to the rising prevalence of metabolic syndrome. Despite sharing a common metabolic background, the association between NAFLD severity and HFpEF has not yet been well explored.Aim: To evaluate the association of NAFLD steatosis and fibrosis scores with cardiovascular function an...