Endocrine Abstracts

Introduction: Primary hyperparathyroidism is a frequent endocrinopathy characterized by a disorder of phosphocalcic metabolism related to an inappropriate secretion of parathyroid hormone (PTH). Parathyroid adenoma can be located ectopically and represents a particular diagnostic and therapeutic challenge. We report 2 clinical cases of ectopic parathyroid adenoma in mediastinal location.Observations: Case 1: A 47-year-old patient without...

Key words: Primary hyperparathyroidism-PTH level –osteoporosis-osteolytic bone lesions-brown tumorIntroduction: Primary hyperparathyroidism is a frequent pathology responsible for an alteration of the phosphocalcic metabolism at the origin of numerous complications, in particular osseous. The objective of this work is to evaluate the bone impact of primary hyperparathyroidism in our series.Matériel et m&#...

Key words: Primary hyperparathyroidsm-Bone complications-Renal complications and digestive complications.IntroductionPrimary hyperparathyroidism is a frequent endocrinopathy whose diagnosis is biological and linked to an inappropriate secretion of parathyroid hormone (PTH), wich leads to an altered phosphocalcic metabolism that can be responsible for numerous complications. The aim of this work is to evaluate the classical complica...

Introduction & Background: Pituitary adenomas represent 10-25% of all intracranial tumors. Their incidence is higher between the ages of 40-60 years and less frequent in young adults. The objective of this work was to evaluate the prevalence as well as the clinical and etiological profile of pituitary adenomas in young adults.Key words : pituitary adenoma- yount adult.Material and methods: Retrospective descriptive study of 21 ...

Key Words: Giant – pituitary adenomaIntroduction & Background: Giant pituitary adenomas are uncommon tumors defined by a tumor diameter ≥ 4 cm. Their prevalence estimated at 6-10% of all pituitary adenomas, whose clinical characteristics and prognosis are not well known. The purpose of this work was to evaluate the prevalence as well as the clinical and evolutionary characteristics of giant pituitary adenomas in our series.<p class="ab...

Introduction: The osteoarticular complications of acromegaly are among most disabling impacts, and can be explained by two mechanisms, chronic exposure to high levels of GH and IGF1 leading to increased bone turnover, hypertrophy and osteocartilaginous degeneration, as well as the gonadal insufficiency observed during acromegaly may aggravate the situation. The objective of this study is to describe the rheumatological manifestations of acromegaly.Materi...

Introduction: Primary hyperparathyroidism is a common endocrinopathy associated with autonomous hypersecretion of PTH by one or more parathyroid glands. This work aims to study the epidemiological, clinical, biological, radiological, and therapeutic profile of primary hyperparathyroidism, as well as its preoperative complications.Material and methods: A retrospective descriptive study of 50 patients followed at the Endocrinology-Diabetology-Nutrition Dep...

Introduction: Pituitary adenomas represent about 10 to 20% of all intracranial tumors. They are usually classified according to their size into pico-adenomas, micro-adenomas and macro-adenomas, but can also be classified according to their secretory properties into secreting or nonfunctional adenomas. In this study, we describe the clinica, paraclinica, therapeutic and evolution features of pituitary adenomas in our center.Material and methods: A retrosp...

Introduction: Metabolic abnormalities are common in pituitary adenomas and metabolic targeting is becoming a new therapeutic approach to the management of most tumor pathologies, especially pituitary tumors. The objective of this work was to assess the metabolic profile of non-functioning pituitary adenomas.Material and methods: A retrospective and descriptive study, over a period of 6 years, conducted in the Endocrinology-Diabetology and Nutrition depar...

Introduction: Primary hyperparathyroidism (PHP) is a common endocrine disease, and its most effective treatment is surgery. Hungry bone syndrome (HBS) is one of the complications that can occur after parathyroidectomy, and that can cause severe and prolonged hypocalcemia. The aim of this study was to determine the risk factors for HBS in patients who underwent parathyroidectomy for PHP.Patients and Methods: This is a retrospective descriptive and analyti...