Searchable abstracts of presentations at key conferences in endocrinology

ea0048cp6 | Poster Presentations | SFEEU2017

The long search for an occult ectopic ACTH-producing tumour

Mills Edouard , Naqvi Ali , Wernig Florian , Todd Jeannie

Case history: Ectopic adrenocorticotropic hormone (ACTH) production accounts for 10–20% of all endogeneous Cushing’s syndrome. The ideal treatment is curative surgery of the underlying tumour. In difficult cases bilateral adrenalectomy is an option. We report a 58-year-old woman with an aggressive ectopic Cushing’s syndrome that required bilateral adrenalectomy undertaken in 1989 at age 32-years.Investigations: At 16 years post adrenalecto...

ea0044oc3.6 | Thyroid and Neoplasia | SFEBES2016

Oestrogens Stimulate Proliferation in Colorectal Cancer via GPER and the Hippo signalling pathway

Arvaniti Anastasia , Gilligan Lorna , Rahman Habibur , Gondal Ali , Foster Paul

Circulating oestrogen concentrations affect the incidence of and outcomes for patients with colorectal cancer (CRC). We have previously shown that steroid sulphatase (STS), the fundamental enzyme that liberates conjugated oestrogens into their active forms, is significantly elevated in human CRC tissue. Here we demonstrate that elevated STS activity correlates to increased CRC proliferation, and that these effects are mediated through G-protein coupled oestrogen receptor (GPER...

ea0044p170 | Neuroendocrinology and pituitary | SFEBES2016

Audit of adult GH replacement therapy in Derby

Yahia Seifeldin , Quah Edmond , Kinton Rebecca , Ali Hisham , Stanworth Roger

Introduction: In 2003, the UK National Institute for Clinical Excellence (NICE) established guidelines on the use of GH in adults. These guidelines state that recombinant GH should be used only for adults with a severe GH deficiency that severely affects their quality of life. To assess current practice in relation to these guidelines, a review of patients receiving GH treatment was performed. The aims were to assess if adults with GH deficiency met NICE criteria for GH therap...

ea0044ep32 | (1) | SFEBES2016

Normocalcemic tetany after parathyroidectomy for hyperparathyroidism

Aziz Umaira , Mallik Ritwika , Ponnampalam Swarupini , Rathore Ali

Introduction: Hypocalcaemia is a frequent complication after thyroid and parathyroid surgery. We report a case of tetany occurred in a patient with normal serum levels of calcium, magnesium and phosphate after parathyroidectomy for hyperparathyroidism.Case History: 55 year old Caucasian male was referred by general physician with three month history of fatigue, loss of appetite, intermittent constipation and abdominal pain. Systemic examination unremarka...

ea0044ep51 | (1) | SFEBES2016

Spontaneous hypoglycaemia in a nondiabetic man with end stage renal disease caused by repaglinide or endogenous hyperinsulinaemia: An enigma entangled

Tauni Rahat Ali , Soo Shiu-Ching , Banerjee Ritwik

A 56 year old man was admitted from psychiatry ward after episode of symptomatic hypoglycaemia with capillary blood glucose of 2.5 mmol/L. His background included CKD on thrice weekly haemodialysis, IHD, stroke, hypertension and paranoid psychosis but not diabetes. He denied taking hypoglycaemics, his oral intake was normal and weight was stable. He had another symptomatic hypoglycamia after 22 hours with venous glucose of 1.5 mmol/L, Insulin 320 mU/L (3.0–17.0) and C-pep...

ea0044ep98 | (1) | SFEBES2016

Thyrotoxic periodic paralysis, and a high carbohyrdate diet; an unusual presentation in a Caucasian male

Ali Tauni Rahat , Arif Rameez , Soo Shiu-Ching

A 54 year old Caucasian male presented with progressive muscle weakness leading to complete paralysis in upper and lower limbs evident on examination. Initial venous gas analysis showed potassium of 2.1 mmol/l, and ECG showed U waves with prolonged QTc. A diagnosis of hypokalaemic periodic paralysis was made, and intravenous potassium administered. The paralysis gradually resolved over the next 3–4 h, as repeat serum potassium level rose to 4.0 mmol/l. He described 6 mont...

ea0043oc34 | Operational Aspects in Diabetes CT's | WCTD2016

Exercise Prescription in Diabetic Patients type 2

Tayebikermani Bahman , Tayebi Behnam , Ali Talebighadikolaei Ghadam , Taghipourdarzinaghibi Mohammad

Sedentary life is one of the main risk factors in diabetes type 2. Exercise and physical activities are very effective in prevention and treatment of diabetic patients. During exercise, muscles uptake more glucose from blood, insulin affects better and glucose is entered easily into the muscular cells. Diabetic Patients can use exercises in order to weight loss, blood glucose control, increasing body capabilities in insulin usage, decreasing body need to drug and insulin injec...

ea0041ep18 | Adrenal cortex (to include Cushing's) | ECE2016

Carotid intima-media thickness as the cardiometabolic risk indicator in patients with nonfunctional adrenal mass and metabolic syndrome screening

Akkus Gamze , Tetiker Tamer , Deniz Ali , Evran Mehtap , Sert Murat

Objective: Nonfunctional adrenal masses are a risk indicator of increased cardiometabolic risk. Especially; increased thrombogenic ambient, insulin resistance, hepatosteatosis and abdominal obesity are determined in these patients with nonfunctional adrenal masses. Our purpose was to show the association of adrenal incidentalome and metabolic syndrome in consideration of the studies and to detect the increase in the carotid intima-media thickness which is regarded as the prece...

ea0041ep193 | Calcium and Vitamin D metabolism | ECE2016

Pregnancy with Fahr’s disease: a rare case report

Gokay Ferhat , Simsek Yasin , Yesiltepe Ali , Dizdar Oguzhan Sitki

Introduction: Fahr’s disease is a rare, neurological disorder characterized by abnormal calcified deposits in basal ganglia. The clinical characteristics are various and usually appears such as disfunction of the affected areas. According to our knowledge, no case of Fahr’s disease together with pregnancy has been described in the literature until now. The objective of this case report was to describe the clinical course of this rare condition in pregnancy.<p cla...

ea0041ep513 | Diabetes complications | ECE2016

Bad eating habits among type II diabetic patients at tertiary hospital: a case-control study

Mansoury Mohammed , Al Zaydi Mohammed , Alwan Ali , Alhusuny Ameer

Background: There is a strong association between type II diabetes mellitus (DM) and gaining weight. Lifestyle modification is an important factor for weight management to overcome the obesity as well as DM epidemics.Aim of study: To find the differences of eating habits and Rosenberg Self-Esteem between DM patients and control and to find the strongest contributor of risk factors by study groups.Methods: A hospital-based matched c...