Searchable abstracts of presentations at key conferences in endocrinology

ea0030p5 | (1) | BSPED2012

A rare case of virilizing adrenocorical carcinoma in a child presented with peripheral precocious puberty

Al-Jumaili Ali

Introduction: Adrenocortical carcioma, is an aggressive cancer originating in the cortex of the adrenal gland. Adrenocortical carcinoma is a rare tumor, in United State <25 new cases of adrenocortical tumours (benign and malignant) are diagnosed annually (0.1–0.4 cases/million per year) and malignant adrenal tumours comprise ~1% of all carcinomas diagnosed prior to 20 years of age. Adrenocortical carcinoma has a bimodal distribution by age, with cases clustering in ch...

ea0021p113 | Clinical practice/governance and case reports | SFEBES2009

Is a morning serum cortisol a useful screening test to rule out hypoadrenalism?

Chakera Ali , Vaidya Bijay

Introduction: A short-synacthen test (SST) is routinely used to diagnose hypoadrenalism, however, some authors suggest using morning serum cortisol as an initial screening test to rule out hypoadrenalism. We assessed the utility of a morning cortisol as a screening test when compared with the outcome of SST.Methods: We retrospectively analysed SSTs carried out in our endocrine outpatient clinic in the last 3 years (649 results). Of these, 113 were identi...

ea0019p148 | Diabetes, Metabolism and Cardiovascular | SFEBES2009

Extreme hypertriglyceridaemia, the therapeutic use of insulin

Naziat A , Chandran S , Ali A

We present a case of a 44-year-old chef, presenting with a fortnight’s history of a pruritic rash over his trunk and axillae. He was diagnosed to have hypertension, which was treated by lifestyle interventions. His diet was poor, and he drank 40 units of alcohol per week. His parents had hypercholesterolemia, but there was no history of premature coronary artery disease. On examination, his BMI was 31.62 kg/m2, and he had eruptive xanthomata on his chest, abdom...

ea0016p174 | Diabetes and cardiovascular diseases | ECE2008

Opportunistic screening for type 2 diabetes mellitus in the out-patient clinic: experience from Basrah, Southern Iraq

Mansour Abbas Ali

Background: Opportunistic screening is more efficient than population screening for diabetes mellitus. The aim is to describe the prevalence of unrecognized diabetes mellitus (DM) among out-patients clinic attending in a major hospital in Basrah, Southern Iraq.Methods: A cross-sectional observational study. The study conducted for the period between January 2006 to end of July 2007. Patients, who attended the out-patient clinic in Al-Faiha hospital in Ba...

ea0073aep867 | Late Breaking | ECE2021

17-β Hydroxysteroid Dehydrogenase Type 3 Deficiency with Novel Mutation in Iranian Family

Saffari Fatemeh , Homaei Ali

IntroductionDeficiency of 17- beta hydroxysteroid dehydrogenase 3 (17-HSD 3) is a rare autosomal recessive disorder which causes sexual ambiguity in fetuses with 46XY karyotype. Pathogenic mutations in the 17βHSD-3 gene (MIM# 264300) are associated with impaired sexual development of the 46, XY fetus. Here, we describe the clinical and genetic findings of a large family with several 46xy cases with a new mutation in 17-β-HSD3 gene in Qazvtn, Ir...

ea0074ncc6 | Highlighted Cases | SFENCC2021

An unusual cause of hypokalaemia: Itraconazole induced apparent mineralocorticoid excess syndrome

Abdalraheem Ali , Seetho Ian

Case history: 81 year-old female was admitted to hospital with pneumonia. Past medical history included laryngeal cancer (1996), laryngectomy, iatrogenic hypoparathyroidism, hypothyroidism, and pulmonary tuberculosis (2007). She was treated with different antibiotics without improvement. She had positive aspergillus serology, but cultures were negative. She was started on voriconazole which was later changed to itraconazole 100 mg twice daily and discharged home. She was seen ...

ea0094p203 | Endocrine Cancer and Late Effects | SFEBES2023

Selective use of mutational analysis helps with diagnostic challenge in hypercalcaemia

Latif Wajeeha , Ali Asif

A 34-year-old was referred for a second opinion regarding his incidental mild hypercalcemia ranging between 2.56 mmol/l and 2.88 mmol/l, with a corresponding PTH ranging between of 3.3 pmol/l and 6.8 pmol/l (laboratory reference range 1.3-9.3 pmol/l). He did not have a history of renal calculi or fractures. He reported chronic recurrent diarrhoea, weight loss, low mood and chronic headache. There was no known family history of calcium disorders. His examination did not reveal ...

ea0094p74 | Metabolism, Obesity and Diabetes | SFEBES2023

Hypoglycemia box awareness among clinical staff - where is the hypoglycemia box?

Butt Saad , Ali Anyat

Hypoglycemia during hospital admission remains a common complication of diabetes. Hypoglycemia is associated with increased morbidity and mortality, increased length of stay, increased admission rate and increased cost to the NHS. Prompt treatment of inpatient hypoglycemia is imperative to avoid such complications. The Hypoglycemia box is an important tool to manage hypoglycemia on the wards. It is crucial for all clinical members to be aware of the hypoglycemia box; its conte...

ea0094p361 | Neuroendocrinology and Pituitary | SFEBES2023

Unusual presentation of suprasellar lesion with adrenal crisis/pan-hypopituitarism but raised tsh

Ali Mudassir , Mada Srikanth

A 44 years old lady with history of suspected psychogenic polydipsia (2021), presented with acute on chronic abdomen pain. She complained of lethargy, intermittent vomiting, abdomen pain, weight loss (four stones) over last six months associated with confusion and visual hallucination since two weeks. She mentioned feeling always thirsty and drinks around 4-5 litres of water per day. Her blood pressure was 87/61 mmHg, heart rate 74/min and U&Es were normal (serum sodium 14...

ea0094p387 | Thyroid | SFEBES2023

Rapid levothyroxine absorption test to diagnose ft4 pseudomalabsorption

Ali Mudassir , Abouglila Kamal

Young man with high BMI and known iatrogenic hypothyroidism, post radioactive iodine (RAI) treatment (2015) for Graves’ thyrotoxicosis (2011) was referred to endocrinology due to significantly raised TSH (at 50 mu/l) and low FT4 (5.0 pmol/l). He was actually admitted with progressive nausea, vomiting over last three weeks. He also complained of abnormal stool consistency (like semi-solid) intermittently. His past medical history also includes gastric bypass with gastro-je...