Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep780 | Calcium and Bone | ECE2024

Exploring the Uncharted Territory: Abacavir in HIV Treatment Unveils Rare Side Effect - A Focus on Hypophosphatemia

Vyas Abhishek , Ali Asad

This case report highlights an unusual side effect of hypophosphatemia linked to Abacavir; a medication commonly used in the treatment of HIV. A 36-year-old male patient was referred to the endocrine team due to persistent hypophosphatemia while receiving Abacavir for his HIV management. Extensive investigations, including assessments of calcium levels Urea and Electrolytes, parathyroid hormone (PTH), Vitamin D, serum magnesium, and serum cortisol and fibroblast growth factor ...

ea0103p52 | Miscellaneous/Other 1 | BSPED2024

Outcomes of children presenting with signs of early puberty to a tertiary paediatric endocrinology service

Ali Mai , Mushtaq Talat

Introduction: Concerns around puberty are a common cause of paediatric endocrinology referrals. This study reviews outcomes of children referred with possible signs of puberty and then provides longitudinal follow up to ascertain the final diagnosis (e.g. premature adrenarche, thelarche, congenital adrenal hyperplasia, or central precocious puberty (CPP))Aims and Objective: The aim was to document the number of children who had a variation of normal pube...

ea0077p230 | Neuroendocrinology and Pituitary | SFEBES2021

Immune check point inhibitor induced hypophysitis with normal pituitary imaging

Ali Tauni Rahat , Ali Khan Amjad , Kehinde Razak

We present a 60-year-old man who was referred to endocrine clinic with fatigue and a random cortisol of 136nmol/l . He had clear renal cell carcinoma and had right radical nephrectomy 7 years ago. Surveillance scans revealed involvement of mediastinal lymph nodes, pancreas and small bowel and he has pancreatic and small bowel resection in four years ago. He had recurrence a year ago and received Ipilimumab and Nivolumab. Biochemistry revealed low fT4 and inappropriately normal...

ea0081p510 | Late-Breaking | ECE2022

Suppressor of cytokine signaling-3 in pregnant females with or without hypertension: a case-control study

Ali Huma , Ali Mubeen , Farhat Sabah , Sadia Fatima Syeda

Suppression of Cytokine Signalling-3 (SOCS-3) modulates the inflammatory pathways responsible for vascular stability by playing a role in inflammatory pathway. It acts by inhibiting the activation of Janus kinase-signal transducer and activating of transcription (JAK-STAT) pathway to transmit their information into the cell nucleus. Therefore, this study aimed to estimate SOCS-3 levels in 2 nd trimester pregnant females and correlate it with blood pressure. A case control stud...

ea0090p697 | Pituitary and Neuroendocrinology | ECE2023

Transphenoidal surgery for sellar and suprasellar lesions: a prospective analysis of factors affecting inpatient length of stay

Ali Mudassir , Olaremi Japhet , Ali Rashid Razan , Mamoojee Yaasir

Background: The recent Get It Right First Time (GIRT) report suggests short stay pathways should be aimed for in pituitary surgery in England, with 1–2 days being realistic. We prospectively audited the length of stay (LOS) for patients undergoing transsphenoidal surgery (TSS) for sellar and suprasellar lesions at the Royal Victoria infirmary hospital (RVI) over a 2-year period, from October 2019.Methods: Data was prospectively collected for each pa...

ea0070aep903 | Thyroid | ECE2020

The effect of ramadan fasting on thyroid function tests: A study of patients on thyroxine replacement therapy

Alkaf Budour , Ali Tomader , Bakir Ali , Lessan Nader

Background: Ramadan fasting entails abstinence of food and drink from dawn to sunset for 30 days. Medication timing also changes; for patients with hypothyroidism this can be a challenge as levothyroxine (LT4) is normally taken on an empty stomach and at least half an hour before breakfast. Complying with this advice during Ramadan is impractical for religious and social reasons. Adverse changes in thyroid function in patients with hypothyroidism have been observed. Whether an...

ea0086p317 | Bone and Calcium | SFEBES2022

A rare case of asymptomatic hyperplastic ectopic parathyroid tissue within the thymus: what are the clinical implications?

Radia Florika , Ali Tauni Rahat

61-year-old-male with a background of treated hypertension and dyslipidaemia presented to accident and emergency with progressive shortness of breath. His most recent bloods were within normal limits. He has a positive family history of cardiac disease, and underwent investigation by CT scanning. This revealed a 10.2 mm anterior mediastinal nodule, which was not avid on PET CT scan. His case was reviewed by the respiratory team and he underwent a left VATs thymectomy. Thymic t...

ea0086p355 | Neuroendocrinology and Pituitary | SFEBES2022

An unusual case of (extremely) delayed ACTH deficiency following pituitary gamma-knife radiotherapy

Radia Florika , Ali Tauni Rahat

59-year-old male, with a background of treated acromegaly, presented to endocrine clinic with new onset fatigue. He was diagnosed with acromegally 18 years prior to his presentation, and had a transphenoidal hypophysectomy followed by gamma-knife radiation. Post-surgery he developed partial anterior hypopituatrism (LH and FSH). He currently takes testosterone replacement. He is still receiving medical management with Somatuline. He developed hypothyroidism 16 years following h...

ea0069p57 | Poster Presentations | SFENCC2020

Severe symptomatic hyponatremia with SIADH picture due to influenza A

Rashid Razan Ali , Bennett Stuart

Case history: A previous healthy 69 year-old female was brought into the ED by her worried husband after he noticed worsening confusion. She developed seizures post arrival to the ED and was admitted under ITU for further care. Retrospective history from the husband indicated she had started feeling unwell around Christmas with a feeling of malaise. She self-medicated with amoxicillin which she had access to as a nurse practitioner. Over the next 2 days she developed headaches...

ea0065p65 | Adrenal and Cardiovascular | SFEBES2019

Maturity onset diabetes of the young: a first case description of PAX4 mutation in the UAE

Boharoon Hessa , El-Houni Ali

Introduction: Maturity-onset diabetes of the young (MODY) is a genetically and clinically heterogeneous type of diabetes mellitus, characterized by early onset (often before 25 years of age) and absence of pancreatic autoimmunity markers.Case: We report a 20 years old female diagnosed with type 1 diabetes at age 18, with positive glutamic acid decarboxylase antibodies and low C peptide level. She had no history of diabetic ketoacidosis or hypoglycemia. H...