Searchable abstracts of presentations at key conferences in endocrinology

ea0094p227 | Metabolism, Obesity and Diabetes | SFEBES2023

Altered glucose homeostasis and the acute porphyrias

Anandhakrishnan Ananthi , Alam Ali , Ramalingam Ramanan

Background: Carbohydrate loading is used to manage the neurovisceral attacks of the acute porphyrias. This presents difficulty when treating those with altered glucose homeostasis.Case history: A 17-year-old female presented with 5 days of abdominal pain and vomiting, her third acute presentation in eight months; the first with a seizure and second with bilateral lower limb weakness. All attendances were preceded by redu...

ea0094p270 | Reproductive Endocrinology | SFEBES2023

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) in pre-eclampsia: A rare case of hyponatraemia in pregnancy

Abdalraheem Ali , Banerjee Ritwik , Thong Lim Chung

Hyponatraemia in pregnancy can be precipitated by various factors, including drugs, fluid excess and oxytocin infusion. It is a common complication of pre-eclampsia toxaemia (PET), although concomitant syndrome of inappropriate ADH secretion (SIADH) in this context is rare. We present a case of SIADH leading to hyponatraemia in a PET patient. A 30 year-old primigravid woman with bipolar disorder and hypertension was admitted with pre-eclampsia at gestational week 28. Her medic...

ea0094p298 | Thyroid | SFEBES2023

A case report of Lithium induced autoimmune thyroiditis in a previously hypothyroid patient

Ali Syed , Elamin Aisha , Robinson Robert

Background: There is a well-documented relationship between lithium exposure and thyroid dysfunction via multiple mechanisms. Lithium is commonly associated with goitre, hypothyroidism, and subclinical hypothyroidism. Lithium-induced autoimmune hyperthyroidism is rare and poorly understood. We report a case of autoimmune thyroiditis, Graves’ disease (GD), in a patient with longstanding primary hypothyroidism believed to be induced by Lithium.<p class=...

ea0050ep024 | Bone and Calcium | SFEBES2017

An Unusual Case of Hypercalcaemia Whilst Severely Hypomagnesaemic

Alkaabi Fatima , Naqvi Ali , Lim Chong , Abbara Ali , Comninos Alexander N , Cox Jeremy

A 68-year-old woman presented with a several month history of nausea, confusion and generalised weakness. In addition, she reported decreased appetite with significant weight loss. She did not report any convulsions, abdominal pain, palpitations, or diarrhoea. Significant past medical history included well-controlled T2DM, hypertension, vitamin D deficiency and GI reflux disease. Importantly, she had no history of renal disease. Relevant medications incl...

ea0050ep024 | Bone and Calcium | SFEBES2017

An Unusual Case of Hypercalcaemia Whilst Severely Hypomagnesaemic

Alkaabi Fatima , Naqvi Ali , Lim Chong , Abbara Ali , Comninos Alexander N , Cox Jeremy

A 68-year-old woman presented with a several month history of nausea, confusion and generalised weakness. In addition, she reported decreased appetite with significant weight loss. She did not report any convulsions, abdominal pain, palpitations, or diarrhoea. Significant past medical history included well-controlled T2DM, hypertension, vitamin D deficiency and GI reflux disease. Importantly, she had no history of renal disease. Relevant medications incl...

ea0038p95 | Clinical practice/governance and case reports | SFEBES2015

Diaphoresis: an unusual initial presenting complaint of Cushing’s syndrome

Ali Sabreen , Abbara Ali , Comninos Alexander , Ramli Rozana , Martin Niamh , Hatfield Emma , Sam Amir , Meeran Karim

Introduction: Diaphoresis, or excessive sweating, is well recognised as a presenting complaint for endocrine disorders such as hyperthyroidism, acromegaly, and phaeochromocytoma. However, diaphoresis is an unusual presenting complaint for Cushing’s syndrome.Case: We present the case of a 35-year-old lady who first presented to health services for symptoms of excessive sweating, and feeling hot most of the time. Whilst initial investigations such as ...

ea0038p124 | Clinical practice/governance and case reports | SFEBES2015

A case of Graves’ disease occurring following cessation of the oral combined contraceptive pill

Ali Sabreen , Abbara Ali , Comninos Alexander , Ramli Rozana , Martin Niamh , Hatfield Emma , Sam Amir , Meeran Karim

Introduction: Graves’ disease is an autoimmune disorder which may lead to thyroid overactivity and eye disease. Oestrogen and progesterone are thought to be immunomodulatory and have been postulated to play an important role in the difference in prevalence of autoimmune disorders between men and women. Autoimmune disorders, including autoimmune thyroid disease, are often quiescent during pregnancy with an increased prevalence postpartum. The increase in immune mediated th...

ea0037ep42 | Adrenal cortex | ECE2015

Phenotypic characteristics of bilateral adrenal masses: about 34 cases

Fedala Nora Soumeya , Haddam Ali El Mahdi , Ali Leyla Ahmed , Benoumechiara Mounia , Chentli Farida , Meskine Djamila

Introduction: Bilateral adrenal tumours are rare and account for 10–15% of adrenal lesions. They can be infectious, inflammatory, tumour, hémmoragiques, and genetic. The clinical and imaging used to guide diagnosis.Aim: Assess clinical, etiologic, and therapeutic characteristics of bilateral adrenal masses.Population and methodology: This is a retrospective study of the records of patients with bilateral adrenal masses co...

ea0037ep43 | Adrenal cortex | ECE2015

Impact of congenital adrenal hyperplasia and glucocorticoid treatment on the final size and gonadal function

Fedala Nora Soumeya , Haddam Ali El Mahdi , Ali Leyla Ahmed , Benoumechiara Mounia , Chentli Farida , Meskine Djamila

Introduction: Congenital adrenal hyperplasia (CAH) are genetic diseases with a deficit of one of the enzymes of steroidogenesis (21 hydroxylase OH, 90%). The consequences of the adrenal hyperandrogenism that results are observed when the treatment is not undertaken precociously.Aim: To study the impact of CAH and or treatment by glucocorticoids on the final size and gonadal function in girls.Materials and methods: 25 patients with ...

ea0037ep44 | Adrenal cortex | ECE2015

Adrenal inclusions in congenital adrenal hyperplasia: clinical and progressive characteristics

Haddam Ali El Mahdi , Fedala Nora Soumeya , Ali Leyla Ahmed , Benoumechiara Mounia , Meskine Djamila , Chentli Farida

Introduction: Intra-testicular adrenal inclusions (ISIT) are benign tumors made of ectopic adrenal cortex tissue hyper stimulated by ACTH in excess. All pathologies causing a rise ACTH levels may be associated with adrenal inclusions. They are found mainly in patients with congenital adrenal hyperplasia (CAH) of untreated or poorly treated.Objective: Search the frequency of ISIT in CAH and clarify clinical and progressive characteristics.<p class="ab...