Endocrine Abstracts

Background: There is a strong association between type II diabetes mellitus (DM) and gaining weight. Lifestyle modification is an important factor for weight management to overcome the obesity as well as DM epidemics.Aim of study: To find the differences of eating habits and Rosenberg Self-Esteem between DM patients and control and to find the strongest contributor of risk factors by study groups.Methods: A hospital-based matched c...

Objectives: We aimed to stratify the possible risk factors for diabetic cardiac autonomic neuropathy (CAN).Methods: We did a metaanalysis of risk factors of CAN. We did a web based search for literature in MEDLINE/PubMed, SCOPUS database, and CENTRAL database up to August 2015. We included clinical trials or cohort studies that provide data about relationship between CAN and variables of interest. Our risk factors of interest were age, sex, duration of d...

Background: There is a strong association between type II diabetes mellitus (DM) and gaining weight. Lifestyle modification is an important factor for weight management to overcome the obesity as well as DM epidemics.Aim of study: To find the differences of eating habits and Rosenberg Self-Esteem between DM patients and control and to find the strongest contributor of risk factors by study groups.Methods: A hospital-based matched c...

Background: Cystic fibrosis related diabetes (CFRD) is associated with deterioration in clinical status. Lung function and nutritional status deteriorate up to 2–4 years before a diagnosis of CFRD based on the oral glucose tolerance test (OGTT). Timely detection and treatment is crucial.Aims: To evaluate: i) adherence to CFRD screening guidelines and ii) whether identifying stages of progressive cystic fibrosis insulin deficiency (CFID) using the ex...

Introduction: Bardet-Biedl syndrome (BBS) is a monogenic disease characterized by retinitis pigmentosa (>90%), obesity (72–86%), insulin resistant diabetes, and hypogonadism. Weight management is challenging due to frequent association of learning and visual impairment. At our BBS MDT clinic, dietetic review is provided at each visit. Dietetic input focuses primarily on reduced fat and sugar content in diet and exercise is encouraged. Individualised written dietary pl...

Background: The investigation of short stature includes evaluation of a number of clinical, radiological, and biochemical factors. This often includes dynamic function testing to rule out abnormalities of the hypothalamic–pituitary axis to rule out GH deficiency (GHD). NICE guidance advises that two GH stimulation tests demonstrating subnormal GH peak <6.7 μg/ml (20 mU/l) is required to confirm the diagnosis of GHD.Objectives: To interrogat...

Aims: To define and identify patients who have ‘failed’ parathyroidectomy by a single surgeon. To explore common features of these cases to refine our pathways.Methods: This case note review began with a retrospective audit of 123 patients having neck exploration from January 2009 to May 2014. The dataset of clinicopathological information obtained from the electronic Trust records, was interrogated to identify patients fulfilling the following...

Endocrinopathies are becoming increasingly recognised with the use of new anticancer drugs. Ipilimumab therapy has recently been associated with hypophysitis. The presentation of hypopituitarism can be non-specific and diagnosis in an oncology setting may be challenging. We describe a 77-year-old man who presented to oncology with a short history of lethargy, nausea, anorexia, and weight loss. He had completed four cycles of ipilimumab as treatment for melanoma 7–9 months...

Background: In steroid dependent patients the knowledge of steroid dose change during illness and stress is of paramount importance.Objectives: i) To assess patient’s knowledge of steroid management during acute illness and stressful condition. ii) To evaluate whether there is a relation between patient knowledge and admission with documented adrenal crisis. iii) To improve medical access to information about patients on steroid at Emergency Departm...

Introduction: Prolactin is a multifunctional pituitary hormone. The effect of prolactin on platelet activation is not well understood. Prolactinomas are the most common type of pituitary adenomas, and they are medically responsive to dopamine agonists. Mean platelet volume (MPV) is a marker of platelet function and activation. The aim of this study was to evaluate MPV values before and 6 months of cabergoline treatment when normoprolactinemia was achieved.<p class="abstext...