Searchable abstracts of presentations at key conferences in endocrinology

ea0077p239 | Reproductive Endocrinology | SFEBES2021

The rate of progression of atherosclerosis in menopause is associated with levels of circulating amyloid beta 1-40

Armeni Eleni , Delialis Dimitrios , Georgiopoulos Georgios , Tual-Chalot Simon , Vlachogiannis Nikolaos , Patras Raphael , Aivalioti Evmorfia , Augoulea Areti , Tsoltos Nikolaos , Soureti Anastasia , Stellos Konstantinos , Stamatelopoulos Kimon , Lambrinoudaki Irene

Background: Cardiovascular disease remains the leading cause of death worldwide, affecting both sexes. Awareness and prevention practices aiming to control cardiovascular risk in women remain inadequate. On the other hand, circulating amyloid β 1-40 (Aβ1-40) is a proatherogenic peptide, closely linked with the process of aging. We aimed to evaluate the possible association between the progression of atherosclerosis in postmenopausal women and the role of Aβ1-40 ...

ea0090p141 | Pituitary and Neuroendocrinology | ECE2023

177Lu DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) in advanced Phaeochromocytomas and paragangliomas (PPGL) – a single centre experience at a ENETS Centre of Excellence

Mansukhbhai Shekhda Kalyan , Armeni Eleni , Hayes Aimee , Caplin Martyn , Toumpanakis Christos , Mandair Dalvinder , Quigley Ann-Marie , Navalkissoor Shaunak , Grossman Ashley , Khoo Bernard

Introduction: Phaeochromocytomas and paragangliomas (PPGL) are rare neuroendocrine tumours with no standardised protocol for treatment. 177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) is an emerging treatment option for patients with metastatic and/or inoperable PPGL, and with low toxicity. We present our experience with PRRT in advanced PPGL, treated in a ENETS Centre of Excellence.Materials and Methods: 165 patients with...

ea0090p469 | Reproductive and Developmental Endocrinology | ECE2023

Gestational thyrotoxicosis due to molar pregnancy complicated by pre-eclampsia

Mansukhbhai Shekhda Kalyan , Zlatkin Vladislav , Kumar Sahoo Saroj , Tamjidul Islam Quazi , Naeem Ammara , Nwokolo Munachiso , Yousseif Ahmed , Karra Efthimia , Patel Dipesh , Khoo Bernard , Armeni Eleni

Introduction: Gestational trophoblastic disease (GTD) is a group of disorders arising from abnormal proliferation of placental trophoblasts. Hydatiform mole (molar pregnancy) is a premalignant condition which is further devided in to partial and complete mole. Incidence of molar pregnancy is estimated to be 1 in 1000 pregnancies. Hyperthyroidism is one of the rare complications of molar pregnancy which, if not detected and treated, can lead to adverse consequences. We describe...

ea0090ep108 | Adrenal and Cardiovascular Endocrinology | ECE2023

Adrenocortical Carcinoma presenting as florid Cushing’s Syndrome

Islam Quazi , Armeni Eleni , Naeem Ammara , Nwokolo Munachiso , Shekhda Kalyan , Karra Efthimia , Khoo Bernard , Patel Dipesh , Sahoo Saroj Kumar , Yousseif Ahmed

Introduction: Adrenocortical Carcinoma (ACC) is a rare endocrine neoplasm with poor prognosis, and an estimated incidence of approximately 2.5/1,000,000 patients. The functional state of these tumors varies from non-secretory (20%) to non-secretory. The latter category is subdivided into glucocorticoid-producing (45%) or glucocorticoid-androgen producing (45%) or androgen-producing only (10%). We report a case of a 35-year-old lady who initially presented with symptoms of Cush...

ea0091wd15 | Workshop D: Disorders of the adrenal gland | SFEEU2023

Uncovering the Rare: Managing a case of ‘Cushing’s Crisis’

Islam Quazi , Armeni Eleni , Khoo Bernard , Mladenova Irinia , Naeem Ammara , Patel Dipesh , Sahoo Saroj , Shekhda Kalyan , Yousseif Ahmed , Grossman Ashley , Karra Efthimia

Introduction: Cushing’s syndrome is a rare endocrine disorder characterized by excess cortisol secretion. It can be caused by various etiologies, including ACTH-dependent and ACTH-independent forms. We report a case of a 78-year-old male who presented with severe hypertension, refractory hypokalemia, and severe hypercortisolaemia, diagnosed with ACTH-dependent Cushing’s syndrome with bilateral adrenal hyperplasia.Case Presentation: A 78-year-ol...

ea0067o49 | Oral Presentations | EYES2019

Genetic background predicts the presence of oligo- or amenorrhea in girls with anorexia nervosa

Augoulea Areti , Armeni Eleni , Paschou Stavroula A , Deligeoroglou Evangelia , Economou Emmanuel , Papadimitriou Georgios , Stergioti Evgenia , Karountzos Vassilios , Tsitsika Artemis , Panoulis Konstantinos , Lambrinoudaki Irene

Objective: To evaluate the association between genetic background and the presence of oligo- or amenorrhea in a sample of adolescent girls diagnosed with anorexia nervosa compared with controls.Methods: A total of 40 adolescent girls diagnosed with anorexia nervosa aged 14–17 years, as well as 10 age-matched girls, were included in the study. We recorded anthropometric parameters and calculated body mass index (BMI) z-scores adjusted for age, as wel...

ea0063gp32 | Diabetes and Cardiovascular Disease | ECE2019

Breastfeeding is inversely associated with subclinical atherosclerosis in postmenopausal women

Kaparos George , Apostolakis Michael , Armeni Eleni , Augoulea Areti , Paschou Stavroula A , Panoulis Konstantinos , Bakas Panagiotis , Georgiopoulos Georgios , Delialis Dimitrios , Deligeoroglou Efthymios , Stamatelopoulos Kimon , Lambrinoudaki Irene

Introduction: The aim of this study was to evaluate the association between a personal history of lactation and indices of subclinical atherosclerosis and arterial stiffness in postmenopausal women.Patients and methods: This cross-sectional study included 283 postmenopausal women. Sonographically assessed indices of vascular function [pulse wave velocity (PWV)] and vascular structure [intima-media thickness (IMT), atherosclerotic plaque presence] were te...

ea0063gp120 | Diabetes: Late Complications | ECE2019

High prolactin levels within the normal range are associated with improved metabolic profile and lower carotid intima media thickness in premenopausal women

Augoulea Areti , Stergiotis Stefanos , Armeni Eleni , Paschou Stavroula A. , Chatzivasiliou Panagiota , Rizos Dimitrios , Kaparos George , Panoulis Konstantinos , Georgiopoulos George , Stamatelopoulos Kimon , Lambrinoudaki Irene

Introduction: A growing body of evidence is supporting a beneficial impact of breastfeeding on maternal metabolism and overall cardiovascular risk. The aim of this study was to evaluate the association between prolactin levels and metabolic parameters as well as indices of subclinical atherosclerosis, in a sample of premenopausal women with normal levels of prolactin.Patients and Methods: This cross-sectional study included a total of 64 non-lactating pr...

ea0063p140 | Diabetes, Obesity and Metabolism 1 | ECE2019

Predictors of incident hypertension in healthy, non-diabetic postmenopausal women with normal renal function

Stamatelopoulos Kimon , Apostolakis Michael , Augoulea Areti , Paschou Stavroula A , Armeni Eleni , Panoulis Konstantinos , Bakas Panagiotis , Georgiopoulos Georgios , Kaparos George , Rizos Dimitrios , Lambrinoudaki Irene

Introduction: The aim of this study was to investigate the incidence of hypertension and to identify potential risk factors in healthy, non-diabetic recently postmenopausal Greek women with normal renal function.Patients and methods: In this retrospective cohort study, we evaluated 141 recently postmenopausal women at baseline and annually thereafter (follow-up time: 1 to 8 years). Blood samples were obtained and ultrasound evaluations were performed at ...

ea0063p217 | Diabetes, Obesity and Metabolism 1 | ECE2019

Metabolic health is strongly predicted by free Testosterone and SHBG levels in non-obese postmenopausal women

Armeni Eleni , Paschou Stavroula A , Augoulea Areti , Rizos Dimitrios , Kaparos George , Soureti Anastasia , Karagouni Iliana , Georgiopoulos Georgios , Stamatelopoulos Kimon , Syggelos Nikolaos , Lambrinoudaki Irene

Introduction: Ovarian senescence and fluctuating levels of sex hormones is associated with metabolic derangement and central obesity. The aim of this study was to explore the association between serum levels of sex hormones and metabolic health in non-obese postmenopausal women.Patients and methods: This cross-sectional study included a total of 457 non-obese postmenopausal (BMI <30 kg/m2) women, retrieved from the Menopause Clinic of Aret...