Searchable abstracts of presentations at key conferences in endocrinology

ea0099p569 | Thyroid | ECE2024

Thyroid core-needle biopsy. first experience in romania. 281 cases with only 1% non-diagnostic results

Mammadov Emin , Terzea Dana , Ciprian Stoicea Mihai

Background: There are two types of thyroid nodule biopsy: fine-needle aspiration (FNAB) and core-needle (CNB). Multiple studies mainly from Eastern Asia demonstrate safety and efficacy of CNB, however it is very rarely used in Europe.Methods: Retrospective analysis of the first 281 CNBs performed in Romania, including 8 lymph nodes and 3 thyroid bed lesions. We used the Korean Thyroid Association reporting system (KTA-CNB) for histology reports.<p cl...

ea0070ep437 | Thyroid | ECE2020

The learning curve of a new thyroid fine-needle aspiration facility

Alexandru Niculescu Dan , Terzea Dana , Deacu Laura , Poiana Catalina

Fine-needle aspiration (FNA) is the best available technique for preoperative diagnosis of malignancy in thyroid nodules. Although its efficiency has been well described, the learning curve is underreported. We aimed to describe the learning curve of a new FNA facility (endocrinologist/pathologist) in a university based hospital.Methods: In February 2018 a new FNA facility was formed in our hospital comprising an endocrinologist with high experience in t...

ea0099ep199 | Endocrine-Related Cancer | ECE2024

A rare case of encapsulated medullary thyroid cancer

Mammadov Emin , Bogdan Sandu Ionut , Terzea Dana , Ciprian Stoicea Mihai

Background: Medullary thyroid carcinoma (MTC) is a rare thyroid tumor (around 2% of thyroid cancers). Its prognosis is generally worse than for differentiated thyroid cancers. A very rare subset of MTC is described as encapsulated MTCs. To date, a limited number of case reports and case series have been published, and this type of tumor presents with no evidence of metastases even in case of very high levels of serum calcitonin.Case: A 33-year old pregna...

ea0081p728 | Thyroid | ECE2022

A rare etiology for thyrotoxicosis − case report

Dumitras Teodor , Patriciu Zubascu Gheorghita , Lucian Mitrache Marius , Miron Adrian , Nitipir Cornelia , Terzea Dana , Fica Simona

Introduction: Hyperthyroidism and thyrotoxicosis can have multiple etiologies, varying from the most frequent described in clinical practice (Graves disease, toxic nodular goiter, thyroiditis) to very rare causes such as anaplastic thyroid cancer, thyroid lymphoma, amyloidosis or even secondary malignancy of the thyroid gland.Case report: A 53 year old man presented to our department for progressive goiter enlargement in the last two months which was acc...

ea0090ep637 | Endocrine-related Cancer | ECE2023

Neuroendocrine carcinoma of the vagina in a young patient – a rare entity

Duta Simona Gabriela , Dumitras Teodor , Sorina Martin Carmen , Cima Luminita , Nitipir Cornelia , Terzea Dana , Fica Simona

Primary vaginal malignancy is uncommon, accounting for about 2% of all gynecological tract cancers, with small-cell neuroendocrine carcinoma of the vagina being exceptionally rare and aggressive. They display similar histological and immunohistochemical features to small-cell carcinomas of different origin. Few cases are reported in the literature so far and therefore, there is no current treatment protocol consensus. We report the case of a 34-year-old nulliparous patient, wh...

ea0063p461 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

Multiple endocrine neoplasia: A case report of a pancreatic neuroendocrine tumor in a long evolving MEN1 patient

Rotarescu Alexandra , Baciu Ionela , Marinescu Mihai , Dumitrascu Anda , Terzea Dana , Poiana Catalina

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare, autosomal dominant inherited syndrome caused by mutations in the MEN1 tumor suppressor gene and is characterized by the occurrence of parathyroid, pancreatic islet and anterior pituitary tumors. We present the case of a female patient known to have pituitary and parathyroid tumors in a MEN1 syndrome evolving for more than 20 years before associating pancreatic neuroendocrine tumor.Case r...

ea0041ep1071 | Thyroid (non-cancer) | ECE2016

Ectopic Thyroid Tissue: Imagery Findings versus Pathological Report

Gheorghisan-Galateanu Ancuta Augustina , Carsote Mara , Dumitrascu Anda , Valea Ana , Geleriu Andreea , Terzea Dana , Ghemigian Adina

Introduction: Accessory thyroid tissue is a part of thyroid dysgenesis and sometime represents an incidental adult finding displaying a normal function.Material and Methods: This is a case presentation of an adult admitted for an atypical anterior cervical aspect which could not be recognized as accessory thyroid tissue only after surgery. Thyroid evaluation used imagery like ultrasound, computed tomography (CT), assays as TSH (Thyroid Stimulating Hormon...

ea0041ep1163 | Thyroid cancer | ECE2016

Biphasic synovial sarcoma: an exceptional rare cervical mass

Ghemigian Adina , Carsote Mara , Petris Rodica , Dumitrascu Anda , Valea Ana , Terzea Dana , Paun Diana Loreta

Introduction: Synovial sarcoma represents a type of cancer derived from soft tissues; young males are more affected.Material and methods: This is a case report of a male with a cervical mass confirmed as sarcoma. Later on the investigations lead to the discovery of a thyroid nodule challenging the differential diagnosis. We assessed thyroid ultrasound, computed tomography (CT) at the cervical, thorax, mediastinum and abdomen; TSH (Thyroid Stimulating Hor...

ea0070aep32 | Adrenal and Cardiovascular Endocrinology | ECE2020

A rare case of functioning adrenocortical oncocytoma of uncertain malignant potential in a young female diagnosed with type 1 neurofibromatosis

Gaita Isabela , Iorgulescu Radu , Cristina Terzea Dana , Danau Razvan , Poiana Catalina , Radian Serban

Background: Adrenocortical oncocytoma is a veryrare adrenal tumor type, usually nonfunctioning and benign. Neurofibromatosistype 1 (NF1) is an autosomal dominant disease caused by mutations of the NF1 gene encoding neurofibromin, a tumor supressor gene that acts by activating a RAS GTP-ase which negatively regulates RAS activity. NF 1 is usually associated with pheocromocytoma, rarely with adrenal carcinoma, and no association with adrenal oncocytoma has been reported.<p c...

ea0070aep536 | Endocrine-related Cancer | ECE2020

Real medical challenges in the diagnostic of gastrinomas

Alexandra Ciobanu Oana , Tieranu Cristian , Terzea Dana , Nistor Irina , Mitrache Marius , Simona Fica

Introduction: Chronic hypergastrinemia is no longer an uncommon phenomenon. Zollinger-Ellison syndrome [ZES], chronic atrophic gastritis [CAG] type A, proton pump inhibitors [PPI] therapy, or Helicobacter pylori-induced CAG type B are causes of hypergastrinemia. Serum gastrin levels >1000 pg/ml (> 0 times the upper limit of normal) and PH gastric below 2 is the diagnostic of ZES, but two -thirds of ZES patients have serum gastrin levels below 1000 pg/ml. We present the...