Endocrine Abstracts

Objective: Stress causes negative effects at all the body especially the heart. As a result of the damage of secreting various hormones which stress cause to secrete in the body. During the stress, respiration, tension, heart speed and catecholamine level increase. All these can be considered as a risk factor for the heart disease. In our study, we aimed to examine stress’ possible histopathological changes on heart muscle.Methods: Eight adult femal...

Objective: Stress, which is seen prevalently among people, causes a general situation of tension via damaging the balance of the body. During stress, it is known that, at the first, central systems, like nerve system, heart and blood circulation system, nutritive system, genital systems and adrenalin tissues are also affected. In this study, kidney was histopathologically examined on the rat model in order to investigate how and in what level the kidneys are affected from the ...

Objective: Placental lactogen (PL) produced by the placenta stimulates lipolysis and fatty acid metabolism in the mother. PL is an anti-insulin hormon. It adjusts the metabolic state of the mother during pregnancy to make easy the energy supply of the fetus. It also reduces maternal tissue sensitivity to insulin, leading to gestational diabetes. A moderate hypertriglyceridaemia due to uncontrolled diabetes may be noticeably worsen by the gestation. As a result, acute hypertrig...

Objective: Unexplained infertility is 15% among all infertility cases. Many forms of stress, including psychological and physical can effect male fertility and reproductive activity. In this study, we aimed to investigate possible histopathological effects of physical and psychological stress on rat testis at light microscopic level.Methods: Eight adult, male Sprague Dawley rats were used in this study. Rats were randomly divided as control (n=4) ...

Objective: Stress has been linked to several diseases. In the course of stress; blood sugar. cortisol and catecholamine levels increase. Visceral hypersensitivity will increase due to catecholaminergic discharges leading to an over-induction of the intrapancreatic secretion. A chronically stress has a role in the induction of insulin resistance in different tissues and pancreas begins to release excessive insulin causing burned out pancreas. For this reason, it becomes insulin...

Introduction: Although pericardial effusion is a common finding in primary hypothyroidism, massive pericardial effusion or pericardial tamponade are rare. Herein, we describe a newly diagnosed case of primary hypothyroidism initially presenting with massive pericardial effusion.Case report: A 64 years old male patient attended to the emergency unit with worsening dyspnea over the past 1 month. ECG showed a low voltage QRS wave. Chest X-ray showed increas...

Introduction: Klinefelter syndrome (KS) is the most common chromosomal disorder characterized by clinical features of hypogonadism and infertility. Portal vein aneurysms are very rare clinic findings. Reported cases are increasing due to use of modern imaging techniques in clinic practise.Case report: 19-year-old man was admitted to our hospital with complaints of abdominal pain, nausea, and vomiting associated with eating. He was recently diagnosed with...

Objective: Agouti related peptide (AgRP), the endogenous antagonist of the melanocortin 3 and 4 receptors, is expressed at high levels in the arcuate nucleus of the hypothalamus. Some studies have demonstrated that intracerebroventricular AgRP administration increases plasma LH, FSH, testosterone levels. It also increases hypothalamic LHRH release in vitro, an effect that can be prevented by addition of melanocyte stimulating hormone. These findings suggest that AgRP ma...

Introduction: Thyroid incidentaloma detected by FDG-PET/CT (flourodeoxyglucose positron emition tomography/computed tomography) is important because of high rate of malignancy. Elastosonograpghy has proven valuable in discriminating malign and benign thyroid lesions. In this study, we aimed to evaluate PET incidentalomas by ultrasonography and elastosonography and to compare cytopathological results with imaging findings.Methods: A total of 50 patients i...

Objective: Different methods are used to identify individuals with insulin resistance. The gold standard is the euglycemic-hyperinsulinemic clamp. However, in clinical practice, clamp is not preferred because it is cumbersome, the HOMA-IR index is used more often. The Trigliserid-glucose (TyG) index is a new and practical way to identify individuals with insulin resistance (IR). When compared to HOMA-IR, this index has been shown to be more reliable in determining insulin resi...