Endocrine Abstracts

Aims: The aim of the present study was to evaluate the relative frequency of histological categories of thyroid malignant neoplasms. Another aim was to evaluate the TNM stage differentiated thyroid carcinoma (DTC) at the time of initial presentation in Valencia Community (Spain).Methods: Histopathology and TNM stage thyroid carcinomas diagnosed of thyroid carcinoma diagnosed between 1998 and 2005 in our endocrinology service, were recorded.The sample was...

Pheochromocytoma (PCC) is a rare tumor that arises from the adrenal medulla, usually presents with headache, sweating and palpitations due to excessive catecholamine release. However, PCC may secrete neuropeptides, hormones and cytokines, such as interleukin-6 (IL-6)) resulting in unusual clinical manifestations. A 48-year-old woman with a previous history of type 1 neurofibromatosis (NF1) and hypertension was referred to discarded PCC. Laboratory tests revealed leukocytosis a...

AimTo establish a relationship between the severity associated with cystic fibrosis transmembrane conductance regulator protein (CFTR) mutations and the prevalence of abnormal glucose tolerance and diabetes in patients diagnosed with cystic fibrosis (CF).MethodsObservational, cross-sectional, clinical research in patients with CF evaluated at Hospital Universitario Reina Sofía (Córdoba).<p class...

AimObesity was shown to be related to global cognitive decline, being especially altered the executive function and the information processing speed. Additionally, sarcopenic obesity (SO) was associated independently with a deterioration in global cognition, executive function, information processing speed, global memory and cerebral atrophy in patients > 65 years. However, at present there is no data regarding the role of sarcopenia in the cognitive...

IntroductionThe term factitious thyrotoxicosis is defined as an excess of thyroid hormone in the body caused by the ingestion of exogenous thyroid hormone. It can be intentional, usually in patients with psychiatric disorders, or accidentally. Another possible cause is the inappropriate use of thyroid hormone for the treatment of obesity, depression or infertility.Case reportWe present the case of a 32-year-o...

IntroductionThe choice of a specialty in medicine is a decision that is imposed on new graduates. The aim of our study was to assess the perception of the specialty of Endocrinology and Nutrition among a large sample of medical students in their final year of their degree or prior to taking their Medical Internship Examination in order to know if they would choose Endocrinology and Nutrition for their specialised training, as well as the most and least a...

IntroductionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has generate a pandemic disease around the world. It has been documented that diabetes mellitus (DM) acts as a risk factor among people hospitalized with coronavirus disease (COVID-19). The objective of this study is to test if DM may unfavorably influence the outcome of COVID-19.MethodsData from Hospital Universitario Central ...

Introduction: E2F1 regulates the expression of genes required for cell cycle progression and apoptosis. miR-17-5p regulates expression of E2F1. Both miR-17-5p and E2F1 have been described deregulated in cancer but they have been scarcely studied in human pituitary neuroendocrine tumours (PitNETs).The aim of the present study was to find biomarkers of aggressiveness in PitNETs and report the correlation between E2F1 and...

Introduction: The metabolic risk associated with air pollution could vary according to the specific pollution levels of each area, as well as factors related to lifestyle (diet, activity physical, socioeconomic status, tobacco), other exposures, comorbidities etc.. and has been insufficiently evaluated in our country.Objective: To study the association between long term exposure to air pollution (measured as PM concentrations) and the incidence of hypert...

Introduction: Catecholamine-secreting tumours derived from the adrenal medulla and the nodes of the autonomic nervous system are known as pheochromocytomas or paragangliomas, respectively. Although their clinical manifestations are similar, their differentiation is important from an epidemiological and prognostic point of view and their possibility of being associated with genetic syndromes.Case report: We present a case of a 16 year old patient, with no...