Endocrine Abstracts

Ovarian function in mammals is regulated by gonadotropins and by sympathetic nervous system. Norepinephrine (NE) is one of the major neurotransmitters present in the fibres innervating the gonad and regulates follicular development and ovarian steroids release. Surgical section of the sympathetic fibres partially decreased the release of NE as compared with non-denervated rats. The remnant release capability supposes the existence of an intraovarian compartment able to incorpo...

BackgroundTranssphenoidal surgery is in general the preferred first-line treatment for patients with macroadenomas except for prolactinomas, which is mainly indicated when the treatment with dopamine agonists (DA) fails. However, in those patients resistant to DA (i.e. volume reduction ObjectiveTo identify predictors of DA resistance in order...

Morbid obesity is associated with a decreased life expectancy and a myriad of serious medical problems. The Roux-en-Y gastric bypass (RYGBP) is the most effective procedure for the treatment of these patients, but it can be responsible of early and late complications. The aim of this prospective study was to evaluate the rate of visceral protein malnutrition (VPM) in morbid obese (MO) patients two years after laparoscopic RYGBP. Albumin (Alb), prealbumin (Prealb), transferrin ...

IntroductionPrediabetes and type 2 diabetes prevalence in children and teenagers has been rising lately, according to obesity increase in this population. Diabetes is the first cause of kidney failure in this individuals. These clinical entities are associated with hypertension and dyslipidemia, leading to an increased risk for cardiovascular disease. In this case, as a result of the presence of a diabetic complication, the differential diagnosis of the ...

Introduction: The introduction of immunotherapy with checkpoint inhibitors for oncologic diseases has improved the survival and quality of life of our patients; however, these therapies are frequently associated with autoimmune endocrine disease.Methods: Revision of the patient’s clinical record and the related literature.Results: Clinical Case : An 88-year old woman was referred to our Endocrinology Clinic because of a PET i...

Introduction/aim: Neurological symptoms are rarely related to decompensated type 2 diabetes mellitus. However, thanks to complementary tests, we can identify this association more easily.Material and method: Review of the patient’s clinical record and the relevant literature.Results: A 76-year old man complained in the last year of a progressive, involuntary and disabling movement disorder consisting in hemichorea of the left...

Aims: The aim of the present study was to evaluate the relative frequency of histological categories of thyroid malignant neoplasms. Another aim was to evaluate the TNM stage differentiated thyroid carcinoma (DTC) at the time of initial presentation in Valencia Community (Spain).Methods: Histopathology and TNM stage thyroid carcinomas diagnosed of thyroid carcinoma diagnosed between 1998 and 2005 in our endocrinology service, were recorded.The sample was...

Introduction: Type 1 diabetes mellitus (T1DM) is considered, in general, a disease of children and young adults with normal body mass index (BMI), linked to a genetic susceptibility based on autoimmunity. However, we know that it can be diagnosed at any age and we must differentiate it from type 2 diabetes mellitus.Objetives: To investigate the phenotypic characteristics and the presence of specific autoimmunity in T1DM patients diagnosed in our hospital...

IntroductionMorbid obesity is a very prevalent disease, bariatric surgery being a fundamental pillar in its treatment.ObjectiveTo analyze the results of weight loss at 1 year in patients operated on gastric bypass and sleeve at the Regional University Hospital (HRU) of Malaga.MethodsRetrospective observational study, with a follow-up period of 1 year, of 215 patie...

IntroductionResponse to Therapy, according to ATA’s dynamic classification, provides a description of the clinical situation in patients with thyroid cancer (TC) a year or more after treatment. It gives us more accurate information than the obtained at diagnosis by static staging systems as AJCC and ATA risk system.ObjetivesTo analyse the association between some factors collected at diagnosis and the ty...