Searchable abstracts of presentations at key conferences in endocrinology

ea0086p20 | Adrenal and Cardiovascular | SFEBES2022

Cortisol/cortisone measurement in sweat samples

Keevil Brian , Marshall David , Adaway Jo , Hawley James

Introduction: Alternative biofluids such as sweat, which can be obtained non-invasively and present a simpler matrix composition than serum/plasma or urine, may be useful for monitoring biomarkers. The long-term sampling with patches either on the chest or back can be conveniently used under both rest and exercise conditions to provide an integrated response of free biomarkers over the course of a day. The smaller sample volumes generated by sweat collection can be convenientl...

ea0065p332 | Neuroendocrinology | SFEBES2019

Recurrent pregnancy induced pituitary apoplexy in a patient with a macro-prolactinoma

Golding Jonathan , Kirresh Omar , Canagon Sara , Sinclair Jo , Wheatley Trevor

A 23-year-old woman was referred with light periods and subfertility with a raised prolactin (1175 miu/l). Remaining pituitary function tests were normal. As she was now pregnant, investigations were postponed until post-pregnancy. Post-partum prolactin was 1823 miu/l and MRI pituitary demonstrated a 13.5 mm pituitary macroadenoma. Cabergoline was commenced but stopped due to a further pregnancy. At 22 weeks gestation she experienced left visual field loss. MRI showed...

ea0049ep1169 | Male Reproduction | ECE2017

Can salivary testosterone be used in the monitoring of men using transdermal testosterone replacement therapy?

Ahern Tomas , Adaway Jo , Monaghan Phillip , Trainer Peter , Keevil Brian

: In community-dwelling men, salivary testosterone (Sal-T) concentrations are thought to represent tissue hormone levels and correlate strongly with serum free-T levels. Measurement of salivary glucocorticoid concentrations is a non-invasive and objective means of assessing cortisol exposure in users and non-users of hydrocortisone therapy. We assessed relationships of Sal-T with transdermal testosterone replacement therapy (TD-TRT) and with markers of testosterone exposure. I...

ea0041ep1166 | Thyroid cancer | ECE2016

Sonographic findings that can be mistaken for thyroid cancer

Kim Tae Hyun , Jo Shin Hyoung , Kim Soonho

Introduction: Thyroid nodule is a common disease that is found in 50% of the adult population; of total, 5% of thyroid nodule cases are diagnosed as thyroid cancers. Thyroid ultrasonography is the most sensitive diagnostic imaging method for the diagnosis of thyroid cancer. The ultrasonographic findings that indicate malignancy are taller than wider, speculate margins, marked hypoechoic lesion, microcalcification, and macrocalcification. In contrast to findings indicating pure...

ea0038p377 | Reproduction | SFEBES2015

Effects of oral, injectable, and implant hormonal contraception on serum levels of iron, ferritin, copper, ceruloplasmin and vitamin E

Samuel Titilola , Morakinyo Olufemi , Balogun Adepeju , Olamijulo Jo , Magbagbeola Olubunmi

Recently there has been reports that the administration of hormonal contraceptives alter the metabolic processes and micronutrients levels. Meanwhile some of these micronutrients are cofactors and or coenzymes of enzymes and are involved in important metabolic pathways. We compared the influence of three contraceptive methods (oral contraceptive, injectables and implants) on serum levels of Iron, ferritin, copper, ceruloplasmin and Vitamin E, using standard methods. Blood samp...

ea0070aep631 | Pituitary and Neuroendocrinology | ECE2020

Functional panhypopituitarism of anorexia

Roque Catarina , Sousa Santos Francisco , Sequeira Duarte João

A 30-year-old male was admitted to the neurotraumatology ward after head trauma with cerebral concussion, subdural & subarachnoidal haemorrhage. The Endocrinologist was called to evaluate high urinary debits. The patient was healthy until 4 years before admission. He enrolled on variate patterns of alimentary restriction that resulted in the loss of 28 kg. Since then he had visited multiple doctors (Cardiology, Haemathology, Psychiatry, Gastroenterology, Urology, Endocrino...

ea0025p1 | Bone | SFEBES2011

Does preoperative localisation for total parthyroidectomy in patients with renal failure improve outcome?

Hanna Thomas , Edwards Jo , Grimsmo Helen , Akoh Jacob

Background: Secondary hyperparathyroidism is a common complication of established renal failure (ERF) and is associated with significant morbidity and mortality. The aims of this study were to determine patient and operative characteristics, which might predict persistent or recurrent hyperparathyroidism after surgery. To assess the influence of pre-operative imaging on the ability to locate and remove parathyroid glands during both the initial and repeat surgery and to assess...

ea0023oc3.1 | Oral Communications 3 | BSPED2009

Accuracy of 2.5 mg hydrocortisone doses from quatered 10 mg tablets

Heames Kirby , Shah Utpal , Riby Phil , Blair Jo , Ford Jim

Introduction: In paediatric practice hydrocortisone (HC) is frequently prescribed in doses of ≤2.5 mg. HC tablets are only available in 10 mg strengths or as 2.5 mg Corlan pellets, a formulation designed for oro-mucosal delivery. Thus, tablets are segmented to obtain an appropriate dose. This study examines the accuracy of obtaining 2.5 mg HC doses from quartered tablets.Materials and methods: Of 10 mg Hydrocortone tablets were studied. Weight unif...

ea0021p325 | Reproduction | SFEBES2009

Pregnancy adversely affects ability to recall previously seen spatial locations

Farrar Diane , Tuffnell Derek , Neill Jo , Marshall Kay

Background: Female sex steroids influence learning and memory and the neurobiology of brain regions involved in memory processing such as the hippocampus. Pregnancy allows overriding of regulatory feedback loops leading to substantial elevation of endogenous serum hormone levels, depending on concentration; oestradiol can be either neurologically protective or toxic. This investigation aimed to increase understanding of the influence of sex steroids on memory and attention dur...

ea0015p4 | Bone | SFEBES2008

Why do we need to think of differential diagnosis?

Myint Thaung , Srinivasan Ram , Randall Jo , Huston Nigel

Fourth-two years old female patient was diagnosed with carcinoma left breast in 2003. She had mastectomy of left breast and axillary clearance followed by adjuvant radiotherapy and chemotherapy. Histology showed ER positive. She was commenced on anastrozole. She suffered from back pain in 2005. Investigations revealed she had spinal metastases as well as left ureteric stone and hydronephrosis of left kidney. She had a left ureteric stent and her back pain was relived. USG kidn...