Endocrine Abstracts

Context: Postpartum hyperthyroidism (PH) is one of the postpartum thyroid disorders that occurs during the first year postpartum and PH is caused by destructive thyroiditis and recurrent Graves’ disease. PH is an exacerbation of an underlying autoimmune thyroiditis that is aggravated by the immunological rebound that follows the partial immunosuppression that occurs during pregnancy. The prevalence of PH among women with Graves’ disease (GD) who had been treated with...

Primary aldosteronism (PA) is a major cause of secondary hypertension. Among PA, the diagnosis of an aldosterone-producing adenoma (APA) is critical because an APA can be cured surgically. Adrenal venous sampling (AVS) is the golden standard test in the diagnosis of an APA, but is available only in specialized medical centers. Meanwhile, aldosterone secretion of an APA is reported to be more sensitive to ACTH than that of idiopathic hyperaldosteronism (IHA) or essential hypert...

Introduction Thyroid cancer (TC) is rare in childhood. The aim of the present study was to describe the tumoral characteristics of children and adolescents with TC and to investigate the frequency of microcarcinomas in that population.Methods We studied the medical records of 101 children and adolescents (≤ 21 years-old) who were diagnosed with TC between January 1977 and December 2011 in Theagenio Cancer Hospital. The following characteristics wer...

Objective: Sex steroids play an important role in the maintenance of bone health. However, there is limited information on the association between sex hormones and age-related bone loss in men. Our objective was to study the relationship between sex steroid levels and the changes accompanying aging process, including bone mineral density (BMD), muscle strength and body composition in elderly Egyptian men.Methods: Free testosterone (FT), estradiol (E...

Grave’s disease is an autoimmune mediated thyrotoxicosis which accounts for 50–80% of cases of hyperthyroidism. In addition to non-thyroid organ involvement, presence of thyroid stimulating hormone receptor antibodies (TRAb) or increased uptake on a nuclear scan are diagnostic. Ultrasound typically shows a diffuse enlargement of the thyroid with increased vascularity, but up to 23% of patients are known to have thyroid nodules. Thyroid nodules carry a 4–6% risk ...

Functional hypothalamic amenorrhoea (FHA) is an endocrine disorder secondary to a deficiency of pulsatile gonadatrophin-releasing hormone (GnRH) secretion. It is not related to hypothalamus-pituitary organic lesions, endocrine or systemic disease. The clinical profile is dependant on the degree of GnRH suppression – it can range from an inadequate luteal phase to hypothalamic amenorrhoea. The incidence of FHA ranges from 15% to 48% of the secondary amenorrheas. We present...

Introduction: Recently published research works have concluded that Covid-19 infection will result in endothelial dysfunction or worsen it, especially when associated with comorbidities such as diabetes mellitus. Arterial Stiffness is a manifestation of endothelial dysfunction and it can be used as a prediction parameter as well as a target for therapies aimed at ameliorating endothelial cell dysfunction.Aims and Objectives: To compare arterial stiffness...

Introduction: Metabolic syndrome (MetS) consists of a constellation of metabolic abnormalities which include central obesity, hyperglycemia plus insulin resistance, high triglycerides plus low high-density lipoprotein (HDL) cholesterol and hypertension. A developing collection of proof proposes that metabolic condition is related to endocrine problems including thyroid brokenness. Thyroid brokenness in metabolic condition patients might additionally add to cardiovascular illne...

65 yr female presented with headaches, heat intolerance and loose stools. She had cerebrovascular accident, osteoporosis and vitiligo. A 24 hr ECG revealed atrial flutter with heart rate upto 117 beats /minute. Her medications include warfarin and bisoprolol.A Thyroid function test (TFT) revealed Free T4 (Ft4): 32 pmol/L (9-19) Free T3: 7.97 pmol/L (3.6–6.5), TSH: 5.7 mU/L (0.35–4.94). Other anterior pituitary function tests were ...

65 yr female presented with headaches, heat intolerance and loose stools. She had cerebrovascular accident, osteoporosis and vitiligo. A 24 hr ECG revealed atrial flutter with heart rate upto 117 beats /minute. Her medications include warfarin and bisoprolol.A Thyroid function test (TFT) revealed Free T4 (Ft4): 32 pmol/L (9-19) Free T3: 7.97 pmol/L (3.6–6.5), TSH: 5.7 mU/L (0.35–4.94). Other anterior pituitary function tests were ...