Searchable abstracts of presentations at key conferences in endocrinology

ea0090p404 | Pituitary and Neuroendocrinology | ECE2023

Prevalence of transient and permanent diabetes insipidus after transsphenoidal pituitary surgery: A systematic review and meta-analysis

Fountas Athanasios , Coulden Amy , Allotey John , Karavitaki Niki

Introduction: Patients undergoing transsphenoidal pituitary surgery (TPS) may develop water balance disorders post-operatively, with diabetes insipidus (DI) being the most common. Nonetheless, data on the prevalence of post-operative DI are not consistent necessitating a systematic review of the literature.Aim: To estimate the prevalence of DI following TPS in patients with pituitary adenomas (PAs), craniopharyngiomas and Rathke’s cleft cysts (RCCs)...

ea0049gp114 | Endocrine Nursing | ECE2017

Outcomes of a nurse-led thyroid clinic at a tertiary-care endocrine centre

Fazal-Sanderson Violet , Karavitaki Niki , Grossman Ashley , Kalhan Atul

Introduction: A Nurse-led Thyroid Clinic (NLTC) in a tertiary-care Endocrinology centre (EC) in Oxford was set up in 2005. The patients were managed by an Endocrine Advanced Nurse Practitioner.Aims: To evaluate standard of clinical care (SOCC) quality of service provision (QOSP) and cost effectiveness (CE) of the NLTC.Methods: Three aspects of service were assessed:a) SOCC: ...

ea0032p232 | Clinical case reports – Pituitary/Adrenal | ECE2013

Bilateral third nerve palsy secondary to an apoplexy in a pituitary macroadenoma causing Cushing’s disease: a very rare complication of a rare entity

Juszczak Agata , Worth Claudia , Karavitaki Niki , Grossman Ashley B

Introduction: Bilateral 3rd nerve palsy is known in conditions such as diabetes mellitus, neurosarcoidosis, Guillain-Barre syndrome, multiple sclerosis, anterior or posterior communicating artery aneurysm or mesencephalic bleed/trauma. There are only single cases reported in association with pituitary adenoma or carcinoma, usually in the context of apoplexy. We describe a patient with Cushing’s disease and bilateral 3rd nerve palsy secondary to apoplexy in pituitary macro...

ea0028p43 | Clinical practice/governance and case reports | SFEBES2012

Disconnection hyperprolactinaemia in non-adenomatous sellar/parasellar lesions practically never exceeds 2000 mU/L

Korevaar Tim , Wass John , Grossman Ashley , Karavitaki Niki

Hyperprolactinaemia in association with a large sellar lesion could represent either tumoural secretion of prolactin (PRL) or stalk disruption by a non-prolactinoma: the differentiation has important therapeutic consequences. We have previously shown that based on currently used assays disconnection hyperprolactinaemia associated with non-functioning adenoma (NFA) practically never exceeds levels above 2000 mU/l. We aimed to verify our proposed disconnection hyperprolactinaemi...

ea0028p157 | Nursing practise | SFEBES2012

Outcome of patients with Graves’ disease after long-term follow-up: data from a Nurse-led Thyroid Clinic

Fazal-Sanderson Violet , Alberts Barbara , Grossman Ashley , Karavitaki Niki

A relapse rate of more than 50% is quoted for patients with Graves’ Disease (GD) treated with anti-thyroid drugs. Our aim was to audit the outcome/relapse rate and possible predictive factors in a series of patients managed in our Nurse-led Thyroid Clinic (NLTC). The notes of patients with newly-diagnosed GD seen in the NLTC between 2005–2011 who had completed 18 months of anti-thyroid drug were reviewed: 60 patients (48 females) were identified. After 18 months of t...

ea0025p42 | Clinical biochemistry | SFEBES2011

A review of the Endocrine Transition Service over the last 10 years

Ray Nilanjana , Davison Tania , Ryan Fiona , Wass John , Karavitaki Niki

Poor transitional care leads to increased loss to follow up, non-adherence to treatment, high morbidity and mortality. The paediatric and adult endocrinology teams in our Trust have been running a joint transition service since 10/2000. A review of this service was undertaken, in order to examine its effectiveness and to aid its improvement.The details of all 81 patients, who had been through transitional care between 10/00-09/09 were acquired. Their rec...

ea0025p68 | Clinical biochemistry | SFEBES2011

Improving communication in clinical care: a re-audit of an Endocrinology and Diabetes GP e-mail advisory service following commissioning

Alberts Barbara , Walker Neil , Karavitaki Niki , Levy Jonathan , Wass John

Introduction and aim: An e-mail based GP advisory service was launched by the authors’ centre in 2005. The PCT commissioned the service in July 2009. Enquiries are handled by specialist registrars with consultant supervision. The charge is £23/enquiry.Pre-commissioning, annual audits demonstrated an efficient and popular service, enhancing communication links between primary and secondary/tertiary care.We re-audited the s...

ea0025p168 | Endocrine tumours and neoplasia | SFEBES2011

Ectopic ACTH syndrome: experience of a tertiary referral centre: from diagnosis to outcome

Veloza Andreia , Ntali Georgia , Wass John , Karavitaki Niki

Introduction: Ectopic Cushing’s syndrome (ECS) accounts for approximately 10% cases of Cushing’s syndrome. Its recognition may be delayed and its diagnosis and treatment remain challenging.Aim: To analyze the clinical, biochemical, radiological features, as well as the outcome of patients with ECS presenting in a tertiary referral centre.Material and methods: The records of patients with ECS followed presenting in our Dep...

ea0025p211 | Nursing practise | SFEBES2011

Nebido (testosterone undecanoate) in patients over 60 years of age: a time to reduce dose frequency?

Mantripp Diana , Franklin Rachel , Wass John , Karavitaki Niki

Background: Clinical experience has shown that men over 60 years of age frequently (40%) require extended intervals of greater than 12 weeks between administrations of Nebido. No work has assessed whether this is specific to men over 60 years of age.Methods: We analysed men on Nebido over 60 years (n=12, mean age 66 years) and compared them with a BMI matched group aged 40–60 years. We assessed testosterone levels, injection intervals, PSA an...

ea0025p286 | Steroids | SFEBES2011

Steroid Replacement Education: Impact on Patients and their Carers

Saeed Mujahid , Aung Theingi , MacDonald Judy , Wass John , Karavitaki Niki

Steroid replacement is life-saving in patients with steroid axis deficiency; education surrounding steroid replacement is vital in their management.We organised ‘Steroid Replacement Education Days’ for patients and their family members/carers to help enhance their knowledge on steroids and intercurrent illness. Lectures detailed manifestations, causes, management of steroid deficiency and the practical issues surrounding steroid replacement. Th...