Endocrine Abstracts

Introduction: Pituitary adenomas represent 10 to 20% of intracranial tumors. In children, craniopharyngioma are the most common tumor of the sellar region. The symptoms can include headache, vomiting, pituitary deficiency and in pituitary adenomas, hormonal excess. The visual examination can find a visual field defect such as a bitemporal hemianopsia. We present a rare case of a pituitary adenoma in a 15-year-old girl with binasal hemianopsia.Observation...

Introduction: Kallmann syndrome is a rare genetic condition characterized by the association of a hypogonadotropic hypogonadism and anosmia. It results from the failure of GnRH cells to migrate to the hypothalamus and lack of development of the olfactory bulb. The main symptom of Kallmann syndrome is delayed or incomplete puberty usually associated with an impaired sense of smell. We herein describe a case of Kallmann syndrome discovered at the age of 57 years old.<p class...

Introduction: The orbit represents the second target after the thyroid gland in autoimmune dysthyroidism. In 80% of cases, endocrine orbitopathy occurs as a result of hyperthyroidism, especially Grave’s disease (GD). Males are rarely affected but the damage is more serious.Observation: We report the case of a 52-year-old patient, an active smoker (35 Pack-Year), transferred from the neurology department for treatment of bilateral malignant exophthal...

A large number of endocrine pathologies can be associated to abnormalities in carbohydrate tolerance up to diabetes. The latter participates in the high risk of cardiovascular morbidity and mortality during these pathologies. The aim of our study was to assess the cardiovascular risk in a diabetic population suffering from an endocrine pathology. This is a retrospective study conducted in the department of endocrinology at Charles Nicolle Hospital involving 54 patients hospita...

Introduction: Although Graves’ disease is often accompanied by other autoimmune diseases, only a few cases of Graves’ disease accompanied by pheochromocytoma have been described.Herein we report a rare case of coexisting Graves’ disease and pheochromocytoma.Observation: A 50-year-old male patient was referred to our department for the evaluation of right adrenal incidentaloma of 80*66 mm. He had a history of coronary...

Introduction: Widespread use of abdominal imaging has led to the identification of an increasing number of adrenal incidentalomas (AI) in the last decades. Causes of these adrenal masses are multiple.Aim: The aim of this study was to investigate the clinical and hormonal characteristics of AI.Materials and methods: The study was a retrospective monocentric analysis of 44 patients with AI who underwent radiographic and endocrine eva...

Introduction: Cardiothyreosis (CT) is the most frequent and dangerous complication of hyperthyroidism (HT). It is defined as an association of HT with severe heart abnormalities such as: rhythmic troubles, heart and/or coronary insufficiency. The aim of our study was to describe the frequency and the clinical characteristics of CT in Graves’ disease (GD).Methods: Patients with GD were enrolled into a retrospective study. The prevalence and the clini...

Introduction: Graves’ ophthalmopathy (GO) is an autoimmune disorder affecting the retro-orbital tissues. It represents the main extra- thyroidal expression of Graves’ disease (GD). Its onset and progression are influenced by several factors that are potentially modifiable. The aim of this study was to identify risk factors for severe GO.Methods: Patients with GD were enrolled into a retrospective study. We compared possible risk factors and var...

Introduction: Metabolic syndrome is closely related to abdominal obesity. Classic anthropometric indices such as bmi and waist circumference have been used for the screening of metabolic syndrome.Recently, it has been reported that waist to height ratio is more closely associated with insulin resistance.The aim of the present study was to assess the relationship between waist to height ratio and components of metabolic syndrome amo...

Introduction: Hemochromatosis is a disorder caused by an excess of iron deposition in the parenchymal cells that leads to organ dysfunction. In patients with secondary hemochromatosis due to multiple blood transfusions, endocrinopathies such as diabetes mellitus, hypopituitarism frequently develop.Herein we report the case of a patient with B-thalassemia major who developed diabetes mellitus, hypopituitarism and primary hypoparathyroidism due to secondar...