Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep1092 | Endocrine tumours | ECE2015

Analysis of current indications to bilateral adrenalectomy

Kurowska Maria , Malicka Joanna , Zwolak Agnieszka , Tarach Jerzy S

Introduction: Bilateral adrenalectomy (BA) is rarely applied as a therapeutic procedure. It serves as a life-saving treatment in patients with persistent Cushing’s disease after an ineffective pituitary surgery or in ectopic ACTH production. Other indications for BA are: bilateral adrenocortical adenomas, congenital adrenal hyperplasia and bilateral phaeochromocytoma in patients with hereditary paraganglioma-phaeochromocytoma (PPS/PGL) syndromes. It is also a procedure of...

ea0037ep1153 | Clinical Cases–Pituitary/Adrenal | ECE2015

Recurrent hyponatremia in woman with undiagnosed postpartum pituitary insufficiency

Kurowska Maria , Malicka Joanna , Zwolak Agnieszka , Tarach Jerzy S

Introduction: Hyponatremia occurs in 33–69% of women with postpartum pituitary necrosis. The aim of the study was to present a patient in whom recurrent hyponatremia was one of the dominant symptoms of postpartum anterior pituitary hormones deficiency.A case report: 55-year-old woman with a diagnosis of Sheehan syndrome established 19 years after the last labor complicated by massive bleeding due to uterine atonia. The first symptoms of pituitary in...

ea0035p715 | Neuroendocrinology | ECE2014

Clinical manifestations of neurofibromatosis type 1

Dabrowska Anna , Zwolak Agnieszka , Kurowska Maria , Tarach Jerzy

Introduction: Neurofibromatosis type 1 (NF1; von Recklinghausen’s disease) is an autosomal disorder with the prevalence 1 in 3,000 births. It is caused by mutation of the tumour-suppressor gene encoding neurofibromin. NF1 may affect various organs and patients are at increased risk of developing many neoplasms.Material and methods: We analysed seven cases of patients with NF1 (four females and three males) aged 19–52 who were treated at Endocri...

ea0026p434 | Thyroid (non cancer) | ECE2011

Autoimmune hyperthyroidism triggered by 131I treatment for toxic nodular goitre: treatment with a second dose of 131I versus thyrostatics

Kijek Jolanta , St Tarach Jerzy , Szymanek Bozena , Kurowska Maria

The transformation of toxic nodular goitre into autoimmune hyperthyroidism with development of thyrotropin receptor antibodies (TSHRAb) as effect of 131I therapy is rarely investigated.The aim of the study is to present cases of patients with toxic nodular goitre who developed autoimmune hyperthyroidism after initial 131I dose, and results of treatment with second 131I dose or thyrostatics.Four pati...

ea0022p222 | Clinical case reports and clinical practice | ECE2010

A retroperitoneal neuroendocrine tumour pre-diagnosed as an adrenal incidentaloma - a case report

Malicka Joanna , Kurowska Maria , Tarach Jerzy , Kijek Jolanta

Introduction: Neoplastic lesions in the retroperitoneum may originate from kidneys, ureters, adrenal glands or peripheral nervous, connective, muscle and adipose tissues. Neuroendocrine tumours are exceptionally located in the retroperitoneum.The case study: A woman aged 51, with a tumour of the left adrenal gland found incidentally during an ultrasound examination of the abdominal cavity, which was performed because of dysuria. A CT confir...

ea0020p122 | Thyroid | ECE2009

The TSH receptor antibody levels (TSHRAb) and thyroid function after 131I therapy in patients with Graves’ disease – 10 years follow-up

Kijek Jolanta , Tarach Jerzy S , Kurowska Maria , Szymanek Bozena

Aim: The aim of the study was the evaluation of the TSHRAb level changes and the comparison with thyroid function in patients with Graves’ disease treated with 131I 10 years ago.Material and methods: The study has been conducted in 67 patients (57 women, 10 men) aged 27–72 y (mean 48 years) with Graves’ disease.All patients were treated with 131I due to hyperthyroidism confirmed by fT3, fT4 and ...

ea0020p123 | Thyroid | ECE2009

The outcome of radioiodine therapy in Graves’ hyperthyroidism: thyroid size as prognostic factor

Kijek Jolanta , Tarach Jerzy S , Kurowska Maria , Jankowska Helena

Aim: The aim of the study was the evaluation of the relationship between thyroid size and the result of radioactive iodine therapy in patients treated due to Graves’ hyperthyroidism.Material and methods: The study group included 150 subjects (127 M and 23 F), aged from 20 to 78 years (mean 48.33 years) at the moment of 131I therapy.In all patients the thyroid technetium-99m scan and determination of the serum levels...

ea0020p155 | Thyroid | ECE2009

Iodine metabolism in hyperthyroidism

Kijek Jolanta , Tarach Jerzy S , Kurowska Maria , Chrapko Beata

Introduction: Iodine is critical for thyroid morphology and function. On the one hand, iodine is a factor leading and permitting to origin of disturbances of thyroid follicular cells function, on the other hand, it’s therapeutic agent.Aim: The aim of the study was to evaluate iodine metabolism in different forms of hyperthyroidism and to analyze relationship between metabolism and thyroid size and function.Material and methods...

ea0016p702 | Thyroid | ECE2008

The outcome of radioiodine therapy of hyperthyroidism: comparison of patients with a toxic nodular goiter and with Graves' disease

Kijek Jolanta , Tarach Jerzy S , Kurowska Maria , Szymanek Bozena

Introduction: Hyperthyroidism is one of frequently encountered clinical syndromes appearing in about 2% of adult population. The aim of this study was to evaluate the efficacy of radioiodine treatment in relation to the form of hyperthyroidism.Material and methods: The study investigated 300 patients: 150 with Graves’ disease and 150 with a toxic adenoma goiter (109 with a solitary nodule and 41 with a multinodular goiter). In all the cases, the est...

ea0056p830 | Pituitary - Clinical | ECE2018

A rare case of acromegaly with normal IGF-1, severe chronic congestive heart failure, and impaired glucose tolerance

Kurowska Maria , Malicka Joanna , Zwolak Agnieszka , Tarach Jerzy S

Introduction: Acromegaly with normal IGF-1level is rarely diagnosed and is difficult to recognize. In acromegalic pa-tients with poorly controlled diabetes, malnutrition, hepatic injury, hepatic congestion due to heart fail-ure, inflammatory diseases, renal dysfunction, and malignant neoplasm, IGF-1 synthesis is inhibited and thus in such cases normal IGF-1 levels may be observed. The aim of the study is to present a rare case of a patient with acromegaly and normal IGF-1 leve...