Searchable abstracts of presentations at key conferences in endocrinology

ea0029oc12.6 | Obesity Clinical | ICEECE2012

Eating speed and the risk of type 2 diabetes mellitus: a case-control study

Radzeviciene L. , Ostrauskas R.

Introduction: Diabetes mellitus is one of the main public health issues. It is becoming a world pandemic. Type 2 diabetes appears to involve interaction between susceptible genetic backgrounds and environmental factors. It’s important to identify modifiable risk factors that may help reduce the risk of type 2 diabetes. For the meantime no data in scientific literature or eating speed could influence on the risk of developing type 2 diabetes mellitus. Therefore the aim of ...

ea0029p350 | Clinical case reports - Pituitary/Adrenal | ICEECE2012

Evaluation on clinical application and long term outcomes of microwave endometrial ablation

Li L. , Luo X.

Study objective: To evaluate the long term outcomes of menorrhagia treated by microwave endometrial ablation(MEA) as well as the factors which influence the outcomes.Design: Prospective, single-arm study.Setting: GuangDong Women’s and Children’s Hospital, GuangDong, China.Patients: Three thirty four women with menorrhagia were selected for MEA, the age of these patients ranged from 29 to 59 years.</...

ea0029p617 | Diabetes | ICEECE2012

Experience of diabetic dyslipidemia correction in patients with ischemic heart disease and type 2 diabetes mellitus using α-lipoic acid in combination therapy

Lopina N. , Zhuravlyova L.

Purposes: To investigate the effects of α-lipoic acid (ALA) on diabetic dyslipidemia, endothelial dysfunction, levels of adiponectin and proinflammatory mediators in combination therapy of patients with ischemic heart disease (IHD) and type 2 diabetes mellitus (T2DM).Methods: We examined 40 patients with IHD and T2DM (19 males, age 60.5±4.7 years). Baseline characteristics of patients included history of IHD (7.2±2.3 years), T2DM (4.7&#177...

ea0029p713 | Diabetes | ICEECE2012

Reducing Residual Vascular Risk Through combination Therapy with Fenofibrate and Alpha-Lipoic Acid in Patients with Ischemic Heart Disease and Type 2 Diabetes Mellitus

Zhuravlyova L. , Lopina N.

Purposes: To investigate effects of combination therapy with fenofibrate and α-lipoic acid (ALA) on atherogenic dyslipidemia, which determines the residual vascular risk and endothelial dysfunction, levels of proinflammatory mediators in patients with ischemic heart disease (IHD) and type 2 diabetes mellitus (T2DM).Methods: We examined 42 patients with IHD and T2DM (19 males, age 60.5±4.7 years). Baseline characteristics of patients included hi...

ea0029p744 | Diabetes | ICEECE2012

The weight reduction could be achieved on DPP-IV inhibitors in very obese T2D patients

Smirnov I. , Zhuravlyova L.

Incretin-based therapy can improve glucose control in type 2 diabetes (T2D) with no weight gain. Usually dipeptidyl peptidase-IV (DPP-IV) inhibitors considered as weight neutral and glucagon-like peptide-1 receptor agonists are associated with weight loss. Some trials showed non-remarkable weight-lowering effect on DPP-IV inhibitors. We aimed to identify patients on DPP-IV inhibitors which are likely to achieve both outcomes either good glycaemic control or weight loss.<p ...

ea0029p903 | Female Reproduction | ICEECE2012

Hormonal contraception and female sexual function

Zilaitiene B. , Ciaplinskiene L.

Summary: To establish the relations of women’s sexual function with social factors and use of hormonal contraception.Methods: There has been performed a pilot study. 20–43 years old participants with regular menstrual cycles (22–35 days) were randomly selected and have been interviewed. The test group consisted of 113 women who use any of hormonal contraception method. The control group consisted of 51 women not using hormonal contraceptio...

ea0029p1254 | Obesity | ICEECE2012

Therapeutic efficacy of obesity treatment methods in teenagers

Viazava L. , Solntsava A. , Sukalo A.

Aim: The aim of our study was to evaluate the effectiveness of the body mass (BM) decreasing program in pubertal children with alimentary obesity during the year of observation.Materials and methods: Anthropometric changes in body mass index (BMI) and waist circumflex (WC) were analyzed every 1, 3, 6 and 12 months in 100 obese pubertal children (boys/girls =50/50) with different treatment methods: the 1st group – only reducing diet (b/g=30/30), the ...

ea0024p40 | (1) | BSPED2010

An audit on the process of transition from the paediatric diabetes service to the adult service at the University Hospital of Wales

Lewis V , Wareing L

Introduction: The period of adolescence is a difficult time for most people and is the time when transition from the paediatric diabetic service to the adult occurs; therefore a smooth transition is essential. The National Service Framework for Diabetes identified transition from paediatric care to adult as an area where protocols could support better care. Placing emphasis on the transition services may help in ensuring effective long-term control and health improvement.<...

ea0019s34 | Phosphoinositide 3-kinase (PI3K) signalling in health and disease: an old system with new potential | SFEBES2009

Signalling from cell surface receptors: molecular mechanisms and physiological significance of the phosphoinositide 3-kinase signalling system

Hawkins P , Stephens L

Phosphoinositide 3-kinase (PI3K) signalling pathways are now accepted to be widely important in the mechanisms by which a variety of cell surface receptors can regulate critical cellular functions, such as cell growth, survival and movement. Class I PI3Ks generate the messenger lipids PtdIns(3,4,5)P3 and PtdIns(3,4)P2 in the inner leaflet of the plasma membrane. These two lipids then co-ordinate the regulation of multiple protein targets by binding, with ...