Searchable abstracts of presentations at key conferences in endocrinology

ea0019p28 | Clinical practice/governance and case reports | SFEBES2009

Hyperglycaemia in a patient with pheochromocytoma

Cho L , Atkin S

A 63-year old woman presented with a 3 weeks history of sweating, panic attacks and vomiting. Urine dipstick on admission was positive for glucose (3+) and ketones (2+) and lab glucose was elevated at 26 mmol/l. Based on the findings she was treated as diabetic ketoacidosis and commenced on insulin. Further investigations showed an elevated urinary catecholamines and marked hypercalcaemia (adjusted calcium 3.10 mmol/l) with unsuppressed PTH at 71 pg/ml (normal 12–72 pg/ml...

ea0015p58 | Clinical practice/governance and case reports | SFEBES2008

An audit of the management of primary hyperparathyroidism

Mahawish L , Peacey SR

We undertook a retrospective audit of patients with primary hyperparathyroidism. Patients were identified from the Bradford Endocrine Database.About 101 patients were identified. 13 were incorrectly labelled and excluded. Case records of 88 patients; median age 64 (range 17–87) years, 69 F:19 M, were examined. At diagnosis median corrected calcium was 2.72 (range 2.45–3.69) mmol/l, median PTH 14 (range 3–182) pmol/l and mean 24 h urine cal...

ea0011s93 | Contrasting practices in European endocrinology | ECE2006

Contrasting practices in European endocrinology. Radioiodine therapy. A Danish view

Hegedüs L

Radioiodine (131-I)- in use for more than 50 years for hyperthyroidism, with or without goitre, and also more recently for non-toxic goitre- has proven effective in the treatment of hyperthyroidism as well as in reducing goitre size. In hyperthyroidism, one or two 131-I doses will cure nearly all patients. Factors such as: sex, age, morphological goitre type, size of goitre, presence of thyroid autoantibodies, and pre- and post-radioiodine antithyroid drug (ATD) therapy influe...

ea0011p107 | Clinical case reports | ECE2006

Co-existing hypoparathyroidism and vitamin D deficiency causing life-threatening hypocalcaemia

Edwards L , Abubaker M

We present a case of a 76-year-old Caucasian woman with combined primary hypoparathyroidism and vitamin D deficiency resulting in life-threatening hypocalcaemia.She has a history of COPD and initially presented in 2002 with an exacerbation of her airways disease. During treatment for her condition an incidental note was made of hypocalcaemia (calcium 1.62 mmol/l). PTH was minimally elevated at the time but 25-hydroxycholecalciferol was low (4.2 ng/ml). S...

ea0011p577 | Neuroendocrinology and behaviour | ECE2006

Dietary supplements for stress and obesity co-morbidities reduction

Dimitrov D , Koeva L

The diet of patients exposed to stress had been shown to be low in fibre, low in fruit and vegetables, low in vitamins C and E, and beta-carotene, high in sugar, and high in saturated fat. The implications of these findings are two-fold: the diet associated with stress is similar to those in patients with features of the Metabolic syndrome (Met-S – visceral obesity, diabetes, hyperlipidemia, hypertension).Aim: The aim of the present study was to ass...

ea0010p95 | Thyroid | SFE2005

Thyroid dysfunction in HIV

Qureshi A , Panahloo A , Seal L

A 54 yr old man presented with a six-month history of palpitations, sweating and weight loss. He had a past history of hypertension, type II diabetes, asthma and was HIV-1 seropositive since 14 yrs and was taking potent anti-retroviral therapy: Nevirapine 200 mg bd; Kaletra 3 capsules bd; and didanosine ec 400 mg od.Investigations confirmed Graves thyrotoxicosis (fT4 72.1 pmol/l; TSH <0.01 mU/l; and TSH receptor antibody positive). He was initially t...

ea0009p5 | Diabetes and metabolism | BES2005

A study of obesity awareness in obese patients attending a District General Hospital

John L , Ooi C

Aims and Methods:Obesity treatment is often unsuccessful despite the efforts of seemingly motivated patients. Awareness among the obese, regarding obesity, is important to facilitate weight loss and to prevent weight gain. We assessed the awareness of obese patients with regard to obesity, its complications and treatment options. Consecutive subjects attending outpatient clinics with BMI>/=30and <70years of age were interviewed.<p class="abstex...

ea0009p71 | Growth and development | BES2005

Effect of grape procyanidins on free radical-induced oxidative damage in MC3T3-E1 Osteoblast-like cells in vitro

Zhong J , Zhang L

Objective: To study the protective effect of grape procyanidins on hydrogen peroxide induced oxidative damage in MC3T3-E1 osteoblast-like cells. Methods: Cultured MC3T3-E1 Osteoblast-like cells were treated with grape procyanidins and 125 micromole per litre hydrogen peroxide for six hours. The levels of apoptosis, mitochondrial transmembrane potential and proliferation were subsequently analyzed by flow cytometry and Bio-Red model 550 instrument. Results: The proliferation le...

ea0009p226 | Clinical | BES2005

An audit on the type and amount of specialist education that newly appionted endocrine nurses receive; educational needs unmet?

Smethurst L , Roberts M

There is an increasing pressure for nurses to have a recognised qualification in their specialist area to be able to use the title 'specialist' nurse. As there is a historical lack of a recognised qualification in endocrinology for nurses, we audited exactly where nurses gained their specialist knowledge in the first year in post.There were no publications on this topic.86 questionnaires designed to allow the individual to rate the...

ea0008dp10 | Diabetes, metabolism and cardiovascular | SFE2004

All men attending diabetes clinics should have serum testosterone measure as it correlates with HDL and sexual dysfunction

Weller A , Seal L

Method: Male diabetic patients attending erectile dysfunction clinic) and general diabetes clinic were studied . Plasma androgen levels were obtained and erectile function assessed using the International Index of Erectile Function (IIEF). Results:Low testosterone showed correlated with increasing age and BMI.Low testosterone correlated with HDL.HbA1c showed positive correlation with intercourse satisfaction....