Endocrine Abstracts

A thorough pre-operative hormonal workup is advised following the recommendations of the European Network for the Study of Adrenal Tumors. Demonstration of endocrine activity may serve to the following purposes: i) prove adrenocortical origin of the mass; ii) suggest malignancy, in the event of androgen hypersecretion; iii) provide tumor markers whose assessment may be exploited during follow-up to detect tumor residual or recurrence after surgery; iv) avoid life-threatening p...

Finding of a firm nodule during palpation of the thyroid gland is one of the clues for malignancy. In addition to palpation, as a new imaging technique, tissue stiffness can be evaluated by ultrasound elastography (USE); thereby helping us further to detect firm thyroid nodules, even the non-palpable ones. Tissue stiffness is detected by USE through measuring the amount of distortion that occurs when the lesions is subjected to external pressure. The power of USE in detecting ...

Pituitary tumours are usually benign, but aggressive local growth may occur. Malignancy with demonstrable extracranial metastases is rarely seen. Tumour formation is probably the result of genetic changes involving tumour suppressor gene inactivation and oncogene activation. Pituitary adenomas that occur in a familial setting account for 4–5% of the tumours, they can be part of endocrine-related tumour syndromes. In 2006, Vierimaa et al.1 reported the re...

We describe case of 50-year patient with poliomyelitis in childhood, no other concomitant ilnesses, admitted in 2010 to neurologic departement of our hospital for grave parkinson-like syndrom with loss of motor function, symetric quadruparesis with spasticity, epileptic seizures and mental deterioration. These problems started about 12 months before and progressively worsened, patient was treated by levodopa and primidone. Patient was after bilateral intraocular lens implantat...

Introduction: Hashimoto’s thyroiditis (HT) and Graves' disease (GD) constitute a spectrum of autoimmune thyroid diseases (AITD). An abnormal thyroid echographic pattern characterized by a diffuse low echogenicity has been described in both AITD. This hypoechogenicity is due to three components: increase of intrathyroidal flow, functional changes in thyroid follicles with increased cellularity and decrease of the colloid content, resulting in the reduction of the cell/coll...

Introduction: A 40-year-old woman, despite previously well controlled Hypothyroidism and Addison’s disease, presented with adrenal crisis due to extremely rare cause.Case Report: In 2002, age 31 years, she presented with symptoms of anorexia, weight loss and postural hypotension. She was subsequently diagnosed to have Addison’s disease and primary hypothyroidism (confirmed with positive adrenal and thyroid peroxidase antibody). She was started ...

Introduction: One of the most important methods for evaluation of treatment and care of diabetic patients is to assess the quality of life (QOL). The aim of this study is assess QOL and this dimensions and relational pattern between demographic characteristic.Method: This study is cross-sectional study wit convenience random sampling. The sample consisted 161 patients with type2 diabetic who refferd to diabetes center of Zanjan. Research instruments was ...

The goal of this research was to analyze fasting glycemic variability in patients with DM1 depending on the type of basal insulin therapy - insulin NPH versus Glargine.Material and methods: The glucose levels 24-hour monitoring was performed applying the CGMS. Glargine group - 19 and NPH group - 24 patients.Results: In the glargine group there have been no episodes of severe fasting hypoglycemia (<2.8 mmol/L), LBGI=2.42±1....

We have come a long way in the UK over the past ten years towards our goal of meeting the educational needs of nurses specialising in adult endocrinology. Endocrine nurses are now able to access annual training updates and attend specific nurse-led sessions at scientific meetings thanks to the ongoing work undertaken by the Society for Endocrinology’s nurse committee.It is therefore time to turn our attention to how we can encourage nurses to want t...

Introduction: A major objective of the ultrasound of thyroid nodules is the stratification of the risk for possible malignancy and the selection of nodules for fine-needle aspiration biopsy (FNAB) and cytological examination.Objective: The objective of this study was to assess the sonographic criteria used in the selection of thyroid nodules for FNAB and to compare them to the cytological reports.Methods/Design: This was a retrospe...