Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep6 | Adrenal and Cardiovascular Endocrinology | ECE2022

Application of machine learning techniques in a qualification for a surgical treatment of adrenal tumors

Wielogorska Marta , Adamski Marcin , Ulychnyi Vitalii , Podgorska Beata , Siewko Katarzyna , Popławska-Kita Anna , Szelachowska Małgorzata , Krętowski Adam , Adamska Agnieszka

Background: The gradual increase in the detection rate of adrenal incidentalomas makes them a common clinical problem. The vast majority of them are benign adrenocortical adenomas. Nevertheless every patient with adrenal incidentaloma requires performing number of tests to exclude pheochromocytoma, autonomous cortisol secretion, adrenal carcinoma and primary hyperaldosteronism. Evaluation of whether adrenal incidentalomas are malignant or functional and continuing patient foll...

ea0081ep18 | Adrenal and Cardiovascular Endocrinology | ECE2022

Cardiovascular risk factors in mild adrenal autonomous cortisol secretion in a Caucasian population

Adamska Agnieszka , Ulychnyi Vitalii , Siewko Katarzyna , Popławska-Kita Anna , Szelachowska Małgorzata , Adamski Marcin , Buczyńska Angelika , Krętowski Adam

Background: Cardiovascular (CVS) risk factors could be present in patients with mild adrenal autonomous cortisol secretion (MACS), which could account for up to 50% of patients with adrenal adenomas. However, the most frequent CVS risk factors in MACS have not been established.Objective: The aim of the present study was to analyse the difference in CVS risk factors in patients with MACS in comparison to those with non-functioning adrenal tumour (NFAT).</...

ea0063gp184 | Benign Thyroid Disorders | ECE2019

Effect of restoration of thyroid function on body composition, insulin resistance and visfatin concentrations in women with hypo- and hyperthyroidism

Sawicka-Gutaj Nadia , Zybek-Kocik Ariadna , Kloska Michal , Czarnywojtek Agata , Sowiński Jerzy , Mańkowska-Wierzbicka Dorota , Ruchała Marek

Introduction: The adipose tissue secrets visfatin, that might have metabolic effect. Changes of visfatin serum concentrations have been observed in different thyroid pathologies. Thyroid hormones affect metabolism, thus, both hypo- and hyperthyroidism might significantly alter body composition.Aims of the study: We aimed to investigate the effect of restoration of euthyroidism on serum visfatin in severe thyroid dysfunction, and its associations with ins...

ea0063gp240 | Anterior and Posterior Pituitary | ECE2019

Adrenal axis deterioration in the families/sporadic patients with PROP1 mutation, over 30 years of single center longitudinal observation

Gilis-Januszewska Aleksandra , Rogoziński Damian , Kluczyński Łukasz , Zygmunt-Gorska Agata , Wojcik Małgorzata , Starzyk Jerzy , Hubalewska-Dydejczyk Alicja

Introduction: The time, degree and mode of pituitary function deterioration in patients with PROP1 mutation is not fully known and understood.Aim: To investigate the time and mode of pituitary function deterioration in the families/sporadic patients with PROP1 mutation during longitudinal observation.Methods: We performed a retrospective longitudinal (33 years, SD=12) analysis of 22 patients (11M/11W) with PROP1 mutation, including...

ea0063p93 | Calcium and Bone 1 | ECE2019

Analysis of non-invasive DXA-derived bone structure parameters in patients with acromegaly with regards to vitamin D levels

Kužma Martin , Vaňuga Peter , Sagova Ivana , Pavai Dušan , Jackuliak Peter , Killinger Zdenko , Binkley Neil , Winzenrieth Renaud , Genant Harry , Payer Juraj

Introduction: Patients suffering from acromegaly, despite normal or even higher bone mineral density (BMD), have prevalent vertebral fractures (VFs). Impaired bone microarchitecture is involved fragility fracture development, but vitamin D status could be involved in this impairment.Aim of the study: Comparison of bone parameters such as BMD, trabecular bone score (TBS) and 3D-SHAPER parameters in acromegaly patients according to level of 25(OH)D3.<p...

ea0063p609 | Diabetes, Obesity and Metabolism 2 | ECE2019

Gut microbiota pattern in relation to diet, physical activity and malnutrition in patients with inflammatory bowel disease: cases-control study

Cornejo-Pareja Isabel , Garcia-Munoz Beatriz , Romero-Perez Eduardo , Garcia-Fuentes Eduardo , Tapia-Paniagua S , Morinigo-Gutierrez MA , Alcain-Martinez Guillermo , Manuel Garcia-Almeida Jose

Introduction: Modifications of gut microbiota have been described in relation to inflammatory bowel disease (IBD), dietary habits and nutritional status.Objective: To relate gut microbial pattern of patients with IBD compared to healthy individuals; and link gut microbial pattern with activity of the disease, nutritional status and dietary habit.Material and methods: Observational study of 56 subjects (44 with IBD and 12 controls)....

ea0063p923 | Diabetes, Obesity and Metabolism 3 | ECE2019

Flash glucose monitoring system in children under 18 years old with diabetes mellitus type 1 in the southern hospital area of Granada: preliminary results

Utrero Sara Leon , Ponce Maria Hayon , Laguna Ma Del Carmen Serrano , Torres Elena Lopez-Mezquita , Charneco Miguel Quesada , Vela Elena Torres

Objective: To evaluate the baseline characteristics and their evolution three months after implantation of the Flash glucose monitoring System (Freestyle Libre), after financing by the Andalusian Health Service in patients under 18 years old with type 1 diabetes mellitus (DM1) in our hospital area.Material and Methods: A descriptive observational and retrospective study that includes patients with DM1 under 18 years old from the southern hospital area of...

ea0063p974 | Diabetes, Obesity and Metabolism 3 | ECE2019

Canagliflozin: Ankle-Brachial index (ABPI) and risk of amputations

Laguna Ma del Carmen Serrano , Ponce Maria Hayon , Utrero Sara Leon , Perez Luisa Sebastian , Torres Enrique Redondo , Charneco Miguel Quesada , Vela Elena Torres

Objectives: Assess the canagliflozin effect on the ABPI in patients without previous treatment with iSGLT-2 as a possible etiology of tissue hypoperfusion and a risk factor for amputations.Material and methods: Prospective observational study where we analyzed patients diagnosed of type 2 diabetes mellitus (DM2) with poor metabolic control and without prior treatment with iSGLT-2, which is initiated treatment with canagliflozin. Clinical, biochemical par...

ea0063p1098 | Pituitary and Neuroendocrinology 3 | ECE2019

The long time observation, treatment modalities and outcomes in patients with childhood/adult onset of craniopharyngioma

Gilis-Januszewska Aleksandra , Kluczyński Łukasz , Rogoziński Damian , Pantofliński Jacek , Zygmunt-Gorska Agata , Wojcik Małgorzata , Starzyk Jerzy , Hubalewska-Dydejczyk Alicja

Background: Craniopharyngiomas are rare, relatively benign, slowly growing intracranial tumors originating in pituitary gland embryonic tissue. They may present at any age, with two peaks of occurrence in children and in older adults. Clinical symptoms are the result of mass effects. Treatment options include surgery, radio- and chemotherapy and unfortunately are connected with a high ratio of postoperative pituitary insufficiency.Aim: To present the lon...

ea0049gp38 | Bone & Calcium Homeostasis 1 | ECE2017

Decreased trabecular bone score but not bone mineral density in patients with acromegaly and concurrent hypogonadism: cross-sectional study with healthy controls

Kužma Martin , Pavai Dušan , Sagova Ivana , Killinger Zdenko , Jackuliak Peter , Vaňuga Anton , Vaňuga Peter , Payer Juraj

Introduction: Acromegaly is associated with higher prevalence of vertebral fractures (VFx) and bone microarchitecture potentially play a role in fracture development. Trabecular bone score (TBS), a novel indicator of bone microstructure could provide additional information.Objectives: Assessment of BMD, TBS and bone turnover markers (BTM) in acromegaly patients in comparison to healthy controls with regard to gender, hypogonadism and disease activity.</p...