Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1474 | Thyroid (non-cancer) | ECE2017

Patient with thyroid carcinoma showing thymus-like differentiation: a case study

Kałużna Małgorzata , Janicki Adam , Sygut Jacek , Marszałek Andrzej , Ziemnicka Katarzyna , Ruchała Marek

Thyroid carcinoma showing thymus-like differentiation (CASTLE) is an extremely rare thyroid neoplasm. This type of tumour may arise from branchial pouch remnants or ectopic thymus and is considered as independent clinicopathological entity of thyroid neoplasms. There have been only about 100 cases described in the literature, so far. Here, we have retrospectively analyzed the data from histopathology and clinics of a 70 year old female patient with thyroid CASTLE who underwent...

ea0037ep624 | Obesity and cardiovascular endocrinology | ECE2015

Levels of advanced glycation end products (AGEs), AGE's receptor (sRAGE) and their relationship with cardiovascular risk factors in newly diagnosed type 2 diabetic patients

Villegas-Rodriguez Etzabel , Solorio-Meza Sergio , Fajardo-Araujo Martha Eugenia , Uribarri Jaime , Malacara Juan Manuel , Torres-Graciano Sofia , Garay-Sevilla Ma Eugenia

Diabetes is associated with a greatly increased risk of cardiovascular disease and the advanced glycation end products (AGEs) and their receptors play an important role in these complications.Objective: To study the association between AGEs and sRAGE levels with cardiovascular risk factors in obese and non-obese newly diagnosed type 2 diabetic patients.Material and methods: We conducted a cross-sectional study in subjects with type...

ea0037ep633 | Obesity and cardiovascular endocrinology | ECE2015

Advanced glycation end products, their receptors RAGE and AGER-1 and their association with insulin resistance and inflammation in obese and non-obese young subjects

Torres-Graciano Sofia , Villegas-Rodriguez Etzabel , Fajardo-Araujo Martha E , Malacara Juan Manuel , Rivera-Cisneros Antonio E , Garay-Sevilla Ma Eugenia

In obesity the combined effects of enhanced food consumption, enhanced oxidative stress and inflammation could increase levels of advanced glycation end products (AGEs) and the action of their receptors.Objective: To study circulating levels of AGEs, soluble RAGE and AGER-1 and their association with insulin resistance and inflammation in young subjects with obesity and normal weight.Material and methods: We conducted a cross-secti...

ea0070aep254 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Chronic activation of adaptive immunity in type 2 diabetes

Garstka Malgorzata , Liu Shan , Ren Xu , Kong Ying , Xu Xiaoqiang , Li Xiaozhen , Jiao Yang , Huang Na , Min Xiaoyun , Ma Ning , Li Baohua , Li Ke , Xu Jing

Context: Type 2 diabetes (T2D) is associated with an increased incidence of infections and several cancers. Although low-grade inflammation and certain immune defects have been found in diabetic patients, the role of adaptive immune response remains to be fully elucidated.Objective: We aimed to explore whether patients with T2D show defects in the activation of T cells.Design: Immune cell phenotypes, T cell functional reactivity, s...

ea0070aep376 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Phase angle (PA) and body composition changes in obese patients with associated comorbidities (by AACE criteria) through a very low calorie diet (VLCD) program

Maria Cornejo Pareja Isabel , Ma Vegas-Aguilar Isabel , Fernández-Medina Beatriz , Tinahones Francisco J , García-Almeida Jose Manuel

Introduction: Obesity is defined as a chronic disease by AACE/ACE. Includes presence/severity of complications. VLCD diets induce relevant weight loss by improving these complications. PA is a bioelectric measure of the cell mass and it is marker a global prognostic factor of cellular functionalism.Methods: Case-control retrospective study of severe obesity in a weight loss program comparing intensive intervention (41 cases, VLCD 800 kcal/d, 1g protein/k...

ea0070aep689 | Pituitary and Neuroendocrinology | ECE2020

Trabecular bone score as a useful tool for assessment of fracture risk in acromegaly

Jawiarczyk-Przybyłowska Aleksandra , Halupczok-Żyła Jowita , Syrycka Joanna , Rolla Małgorzata , Zembska Agnieszka , Kubicka Eliza , Bolanowski Marek

Acromegaly is a rare disease, caused by an excessive secretion of growth hormone (GH), and consequently the insulin like growth factor 1 (IGF-1). Patients with acromegaly have an increased risk of fractures, which might be correlated with insufficient quality of bone. It is known that use of FRAX in acromegaly is not validated, however we do not have other useful tools to assess real risk for fractures. The new valuable tool in the assessment of bone structure is the trabecula...

ea0032p79 | Bone and Osteoporosis | ECE2013

Impact of the FRAX® tool and the NOGG guidelines on the indication of bone mineral density in Spanish postmenopausal women

Kyriakos Georgios , Casariego Alfonso Vidal , Turcios Dalia Avila , Moreno Ana Hernandez , Fernandez Alicia Calleja , Suarez Ma Dolores Blanco , Taibo Rocio Villar , Pomar Maria D. Ballesteros , Rodriguez Isidoro Cano

Introduction: The National Osteoporosis Guideline Group (NOGG) recommends determine BMD in patients who present an intermediate risk of osteoporotic fracture using the FRAX® tool, follow-up for low risk, and treatment for high risk. In 2011, 3163 BMD were performed in the Complejo Asistencial Universitario de León (CAULE). Since the cost for each BMD is 58.6* (BOCYL 31/01/2011), annual spending could rise to *185 352. The aim was to assess whether fracture risk calcu...

ea0032p123 | Calcium and Vitamin D metabolism | ECE2013

Early measure of postoperative iPTH and corrected calcium as predictors of future hypoparathyroidism: which, when and why?

Paja Miguel , Moreno Cristina , Ugarte Estibaliz , Oleaga Amelia , Gutierrez Ma Teresa , Izuzquiza Ana J , Etxeberria Eider , Iglesias Natalia C , Lizarraga Aitzol , Martinez-Mate Maria P

Introduction: Intraoperative parathyroid hormone assay (ioPTH) has been validated as a useful tool for predicting postoperative hypocalcaemia (hypoCa) after thyroid surgery and has been proposed as a guide to early discharge from hospital. Its value to predict the risk of future hypoparathyroidism (hypoPT) has not been analyzed in detail. We evaluate this role in our recent surgical series.Description of methods/design: Patients with total thyroidectomy ...

ea0029p762 | Endocrine Disruptors | ICEECE2012

The effects of BPA exposure on fat mass and serum leptin concentrations have no impact on bone mineral densities in non-obese premenopausal women.

Liu J. , Zhao H. , Bi Y. , Ma L. , Zhang L. , Zhao L. , Tao B. , Sun L. , Wang T. , Zhao Y. , Wang W. , Xu M. , Chen J. , Ning G.

Objective: Bisphenol A (BPA) exposure may promote obesity, but its effect on bone mineral density (BMD) has not been reported in humans. In the present study, we aimed to examine the complex interplay between BPA exposure, fat mass, fat-free mass, serum estradiol, leptin, osteocalcin levels and BMDs in a group of premenopausal women.Methods: A total of 246 Chinese premenopausal women aged 20 years and older with regular menstrual cycles were investigated...

ea0016p605 | Reproduction | ECE2008

The relationship between semen parameters and blood hormone in men with congenital absence of vas deferens

Ren-Qian Wen , Li-Xin Tang , Shun-Mei Deng , Yang-Jia Jiang , Qi-Ling Wang , Ai-Ping Cheng , Chun-Jie Ma , Fang Jiang , Zhu-Lin Miao

Aim: To investigate the ralationship between semen parameters and serum follicale-stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), prolactin (PRL) in a group of Chinese men with congenital absence of vas deferens (CAVD).Methods: Ninety patients with CAVD were investigated. During the physical examination the body hair distribution, testicular size, epididymides and vas deferens were carefully inspected and palpated. Semen analysis i...